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Report of the American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes and clinical trial coordination. The Consensus Committee.

Bernard, GR and Artigas, A and Brigham, KL and Carlet, J and Falke, K and Hudson, L and Lamy, M and LeGall, JR and Morris, A and Spragg, R (1994) Report of the American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes and clinical trial coordination. The Consensus Committee. Intensive Care Med, 20 (3). 225 - 232. ISSN 0342-4642

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Abstract

The acute respiratory distress syndrome (ARDS), a process of non-hydrostatic pulmonary edema and hypoxemia associated with a variety of etiologies carries a high morbidity, mortality (10-90%) and financial cost. The reported annual incidence in the United States is 150,000 cases, but this figure has been challenged and may be different in Europe. Part of the reason for these uncertainties is the heterogeneity of diseases underlying ARDS and the lack of uniform definitions for ARDS. Thus, those whose wish to know the true incidence and outcome on this clinical syndrome are stymied. The European American Consensus Committee on ARDS was formed to focus on these issues and on the pathophysiologic mechanisms of the process. It was felt that international coordination between North America and Europe in clinical studies of ARDS was becoming increasingly important in order to address the recent plethora of potential therapeutic agents for the prevention and treatment of ARDS.

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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Bernard, GR
Artigas, A
Brigham, KL
Carlet, J
Falke, K
Hudson, L
Lamy, M
LeGall, JR
Morris, A
Spragg, R
Contributors:
ContributionContributors NameEmailPitt UsernameORCID
Committee MemberPinsky, Michael Rpinsky@pitt.eduPINSKYUNSPECIFIED
Date: 1994
Date Type: Publication
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Journal or Publication Title: Intensive Care Med
Volume: 20
Number: 3
Page Range: 225 - 232
DOI or Unique Handle: 10.1007/bf01704707
Institution: University of Pittsburgh
Schools and Programs: School of Medicine > Critical Care Medicine
Refereed: Yes
Uncontrolled Keywords: Clinical Protocols, Clinical Trials as Topic, Europe, Forecasting, Goals, Health Care Costs, Humans, Incidence, Morbidity, Prevalence, Respiratory Distress Syndrome, Risk Factors, Treatment Outcome, United States
ISSN: 0342-4642
Funders: NHLBI NIH HHS (NHLBI 19153), NHLBI NIH HHS (NHLBI HL ROI 43167)
Date Deposited: 05 Mar 2012 17:51
Last Modified: 20 Dec 2020 03:55
URI: http://d-scholarship.pitt.edu/id/eprint/11181

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