Left ventricular pressure-volume relations with transesophageal echocardiographic automated border detection: Comparison with conductance- catheter technique

Gorcsan, J and Denault, A and Mandarino, WA and Pinsky, MR (1996) Left ventricular pressure-volume relations with transesophageal echocardiographic automated border detection: Comparison with conductance- catheter technique. American Heart Journal, 131 (3). 544 - 552. ISSN 0002-8703

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Abstract

Pressure-volume relations are important means used to assess left ventricular (LV) contractility; however, on-line volume acquisition has been limited to the invasive conductance catheter. The objective was to compare simultaneous measures of LV volume by transesophageal echocardiographic automated border detection (ABD) and conductance catheter and their respective pressure-volume relations during steady state and alterations in preload and contractility. Seven dogs had placement of high-fidelity pressure end conductance catheters, a vena caval balloon occluder, and a transesophageal probe. An automated Simpson's rule volume algorithm was used from the transverse four-chamber view. Inotropic modulation was induced with dobutamine in four dogs and propranolol in three. Relative changes in ABD volume were linearly related to conductance volume at steady state with group mean r = 0.93 ± 0.03, standard error of estimate (SEE) = 10 ± 2%. Changes in end-diastolic volume, end-systolic volume, and stroke work with caval occlusion were also significantly correlated: r = 0.93 ± 0.04, SEE = 3,6 ml; r = 0.89 ± 0.04, SEE = 3.8 ± 1.9 ml; and r = 0.86 ± 0.05, SEE = 40 ± 21 mJ, respectively. The overall bias was for absolute ABD volume to be less. End-systolic and maximal elastance values by ABD were significantly higher than by the conductance method; baseline group average 4.97 ± 0.92 mm Hg/ml versus 2.70 ± 1.15 mm Hg/ml and 6.63 ± 1.66 mm Hg/ml versus 3.20 ± 1.37 mm Hg/ml (p < 0.05), respectively. However, the direction and relative magnitude of changes in elastance with inotropic modulation were similar.

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Details

Item Type:	Article
Status:	Published
Creators/Authors:	Creators Email Pitt Username ORCID Gorcsan, J gorcsan@pitt.edu GORCSAN Denault, A Mandarino, WA Pinsky, MR pinsky@pitt.edu PINSKY 0000-0001-6166-700X
Date:	1 January 1996
Date Type:	Publication
Journal or Publication Title:	American Heart Journal
Volume:	131
Number:	3
Page Range:	544 - 552
DOI or Unique Handle:	10.1016/s0002-8703(96)90535-9
Schools and Programs:	School of Medicine > Critical Care Medicine
Refereed:	Yes
ISSN:	0002-8703
PubMed ID:	8604636
Date Deposited:	05 Mar 2012 19:52
Last Modified:	30 Jan 2020 16:55
URI:	http://d-scholarship.pitt.edu/id/eprint/11230

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