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Utility of echocardiographic radial strain imaging to quantify left ventricular dyssynchrony and predict acute response to cardiac resynchronization therapy

Dohi, K and Suffoletto, MS and Schwartzman, D and Ganz, L and Pinsky, MR and Gorcsan, J (2005) Utility of echocardiographic radial strain imaging to quantify left ventricular dyssynchrony and predict acute response to cardiac resynchronization therapy. American Journal of Cardiology, 96 (1). 112 - 116. ISSN 0002-9149

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Abstract

Echocardiographic strain imaging was used to quantify radial mechanical dyssynchrony in 38 patients who underwent cardiac resynchronization therapy. Dyssynchrony, defined as the time difference of peak radial strain in the septum versus the posterior wall, was significantly greater in patients with acute hemodynamic responses, and changes in radial dyssynchrony correlated with changes in stroke volume. A <130-ms difference in septal versus posterior wall peak strain when combined with a favorable left ventricular lead position was strongly predictive of immediate improvement in stroke volume with resynchronization therapy (95% sensitivity, 88% specificity), regardless of electrocardiographic QRS duration. © 2005 Elsevier Inc. All rights reserved.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Dohi, K
Suffoletto, MS
Schwartzman, D
Ganz, L
Pinsky, MRpinsky@pitt.eduPINSKY
Gorcsan, Jgorcsan@pitt.eduGORCSAN
Date: 1 July 2005
Date Type: Publication
Journal or Publication Title: American Journal of Cardiology
Volume: 96
Number: 1
Page Range: 112 - 116
DOI or Unique Handle: 10.1016/j.amjcard.2005.03.032
Schools and Programs: School of Medicine > Critical Care Medicine
Refereed: Yes
ISSN: 0002-9149
PubMed ID: 15979447
Date Deposited: 05 Apr 2012 21:55
Last Modified: 04 Feb 2019 15:56
URI: http://d-scholarship.pitt.edu/id/eprint/11583

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