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Informal caregiver burden among survivors of prolonged mechanical ventilation

Van Pelt, DC and Milbrandt, EB and Qin, L and Weissfeld, LA and Rotondi, AJ and Schulz, R and Chelluri, L and Angus, DC and Pinsky, MR (2007) Informal caregiver burden among survivors of prolonged mechanical ventilation. American Journal of Respiratory and Critical Care Medicine, 175 (2). 167 - 173. ISSN 1073-449X

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Rationale: Although caregiver burden is well described in chronic illness, few studies have examined burden among caregivers of survivors of critical illness. In existing studies, it is unclear whether the observed burden is a consequence of critical illness or of preexisting patient illness. Objectives: To describe 1-yr longitudinal outcomes for caregivers of patients who survived critical illness, and to compare depression risk between caregivers of patients with and without pre-intensive care unit (ICU) functional dependency. Methods: Prospective, parallel, cohort study of survivors of prolonged (greater than 48 h) mechanical ventilation and their informal caregivers. Caregivers were divided into two cohorts on the basis of whether patients were functionally independent (n = 99, 59%), or dependent (n = 70, 41%) before admission. Functional dependency was defined as dependency in one or more activities of daily living or in three or more instrumental activities of daily living. Patient and caregiver outcomes were measured 2, 6, and 12 mo after mechanical ventilation initiation. Measurements and Main Results: We studied three caregiver outcomes: depression risk, lifestyle disruption, and employment reduction. Most patients were male (59.8%), with a mean (SD) age of 56.6 (19.0) yr. Caregivers were mostly female (75.7%), with amean (SD) age of 54.6 (14.7) yr. Prevalence of caregiver depression risk was high at all time points (33.9, 30.8, and 22.8%; p = 0.83) and did not vary by patient pre-ICU functional status. Lifestyle disruption and employment reduction were also common and persistent. Conclusions: Depression symptoms, lifestyle disruption, and employment reduction were common among informal caregivers of critical illness survivors. Depression risk was high regardless of patient pre-ICU functional status.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Van Pelt, DC
Milbrandt, EB
Qin, L
Weissfeld, LA
Rotondi, AJ
Schulz, Rschulz@pitt.eduSCHULZ
Chelluri, L
Angus, DCangusdc@pitt.eduANGUSDC0000-0002-7026-5181
Pinsky, MRpinsky@pitt.eduPINSKY0000-0001-6166-700X
Date: 23 January 2007
Date Type: Publication
Journal or Publication Title: American Journal of Respiratory and Critical Care Medicine
Volume: 175
Number: 2
Page Range: 167 - 173
DOI or Unique Handle: 10.1164/rccm.200604-493oc
Schools and Programs: School of Medicine > Critical Care Medicine
Refereed: Yes
ISSN: 1073-449X
PubMed Central ID: PMC1899280
PubMed ID: 17068327
Date Deposited: 05 Apr 2012 21:12
Last Modified: 30 Jan 2020 16:55


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