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Multiple systems organ failure: failure of host defense homeostasis

Pinsky, Michael R and Matuschak, GM (1988) Multiple systems organ failure: failure of host defense homeostasis. In: Recent advances in anesthesia, pain, intensive care and emergency. UNSPECIFIED, 219 - 222. ISBN UNSPECIFIED

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Abstract

To understand the processes involved in the development of MSOF, we will first define what is meant by the terms sepsis, shock, MSOF, malignant intravascular inflammation, proinflammatory mediator, and immunocompromised host. We will then briefly discuss manifestations of single organ system failure as they relate to the expression of MSOF, offering as we do, hypotheses with regard to the basic mechanisms of MSOF. Finally, because infection and host response to it appear to be central in the development of MSOF, we will discuss the pathophysiology of septic shock.


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Details

Item Type: Book Section
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Pinsky, Michael Rpinsky@pitt.eduPINSKY
Matuschak, GM
Date: 1988
Date Type: Publication
Volume: 3
Page Range: 219 - 222
Schools and Programs: School of Medicine > Critical Care Medicine
Refereed: Yes
Title of Book: Recent advances in anesthesia, pain, intensive care and emergency
Editors:
EditorsEmailPitt UsernameORCID
Mocavero, GUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gullo, AUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Paladini, VAUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Romano, EUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
PubMed ID: 2650814
Date Deposited: 12 Jul 2012 21:57
Last Modified: 01 Nov 2017 14:05
URI: http://d-scholarship.pitt.edu/id/eprint/11732

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