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The effects of mechanical ventilation on the cardiovascular system

Pinsky, MR (1990) The effects of mechanical ventilation on the cardiovascular system. Critical Care Clinics, 6 (3). ISSN 0749-0704

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Positive-pressure ventilation may improve gas exchange, decrease the work-cost of breathing, and rest respiratory muscles, but it also will alter cardiac output and may modify blood flow distribution. Ventilation may induce these hemodynamic changes by altering systemic venous return to the RV (RV preload), pulmonary arterial pressure (RV after-load), ventricular interdependence (LV preload), or transmural LV ejection pressure (LV afterload). These interactions are magnified when the changes in lung volume and intrathoracic pressure are increased or under conditions associated with a reduced effective circulating blood volume or cardiac contractility. An understanding of these interactions is central to the effective management of the ventilator-dependent patient.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Pinsky, MRpinsky@pitt.eduPINSKY0000-0001-6166-700X
Date: 1 January 1990
Date Type: Publication
Journal or Publication Title: Critical Care Clinics
Volume: 6
Number: 3
DOI or Unique Handle: 10.1016/s0749-0704(18)30360-9
Schools and Programs: School of Medicine > Critical Care Medicine
Refereed: Yes
ISSN: 0749-0704
Article Type: Review
PubMed ID: 2199000
Date Deposited: 12 Jul 2012 21:36
Last Modified: 03 Aug 2020 13:56


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