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Searching for non-invasive markers of tissue hypoxia

Puyana, JC and Pinsky, MR (2007) Searching for non-invasive markers of tissue hypoxia. Critical Care, 11 (1). ISSN 1364-8535

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Tissue hypoxia is a common end product of circulatory shock and a primary target for resuscitation efforts. In this issue Podbregar and Mozina show that thenar tissue O2 saturation (StO2) and mixed venous O2 saturation (SvO2) co-vary in patients in left ventricular failure, but in patients with sepsis StO2 was higher than SvO2. Although StO2 may co-vary with SvO2 they have different determinants such that after shock StO2 may increase well before SvO2 as a result of increased O2 demands to repay O2 debt incurred during hypoperfusion. Thus, the use of StO2 alone to define the endpoint of resuscitation may be misleading. © 2007 BioMed Central Ltd.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Puyana, JC
Pinsky, MRpinsky@pitt.eduPINSKY0000-0001-6166-700X
Date: 23 February 2007
Date Type: Publication
Journal or Publication Title: Critical Care
Volume: 11
Number: 1
DOI or Unique Handle: 10.1186/cc5691
Schools and Programs: School of Medicine > Critical Care Medicine
Refereed: Yes
ISSN: 1364-8535
PubMed Central ID: 2151870
PubMed ID: 17331268
Date Deposited: 14 Jul 2012 16:46
Last Modified: 22 Jun 2021 14:55


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