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Patient-specific, time-varying predictors of post-ICU informal caregiver burden: The caregiver outcomes after ICU discharge project

Van Pelt, DC and Schulz, R and Chelluri, L and Pinsky, MR (2010) Patient-specific, time-varying predictors of post-ICU informal caregiver burden: The caregiver outcomes after ICU discharge project. Chest, 137 (1). 88 - 94. ISSN 0012-3692

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Background: The outcomes of informal caregivers of survivors of critical illness likely depend on patient characteristics, which may change over time. To date, few studies have examined patient-specific predictors of post-ICU informal caregiver burden, and none has tested whether predictors vary after hospital discharge. Methods: We designed a prospective, longitudinal observational study, enrolling 48 patient-caregiver dyads from four ICUs in a university hospital. Informal caregiver depression symptoms were measured with the Center for Epidemiologic Studies Depression scale. Lifestyle disruption was measured with the Activity Restriction Scale. Linear regression models were built to test for patient- and caregiver-specific predictors of depression symptoms and lifestyle disruption 2, 6, and 12 months after ICU admission. Results: Patients had a mean (SD) age of 52.5 (19.7) years, 67% were men, median (interquartile range) Acute Physiology and Chronic Health Evaluation score was 52 (38.5, 65). The caregivers had a mean (SD) age of 52.8 (12.8) years, 91.2% were women, and 48% were spouses. Predictors of caregiver depression symptoms were patient gender (men) at 2 and 12 months and tracheostomy at 12 months. Predictors of lifestyle disruption were patient education (more common among high school graduates) and patient gender (men) at 2 months, and tracheostomy, functional dependency, and patient gender (men) at 12 months. Conclusions: The determinants of post-ICU informal caregiver burden likely depend on characteristics of the patient as well as the caregiver and may vary over time. Further research is necessary to better understand the longitudinal determinants of burden in order to develop more effective caregiver interventions. © 2010 American College of Chest Physicians.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Van Pelt, DC
Schulz, Rschulz@pitt.eduSCHULZ
Chelluri, L
Pinsky, MRpinsky@pitt.eduPINSKY0000-0001-6166-700X
Date: 1 January 2010
Date Type: Publication
Journal or Publication Title: Chest
Volume: 137
Number: 1
Page Range: 88 - 94
DOI or Unique Handle: 10.1378/chest.09-0795
Schools and Programs: School of Medicine > Critical Care Medicine
Refereed: Yes
ISSN: 0012-3692
PubMed Central ID: 2803119
PubMed ID: 19762552
Date Deposited: 14 Jul 2012 16:10
Last Modified: 30 Jan 2020 16:55


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