Lopez, FA and Crowley, Rebecca S and Wastila, L and Valantine, HA and Remington, JS
(1998)
Scedosporium apiospermum (Pseudallescheria boydii) infection in a heart transplant recipient: a case of mistaken identity.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 17 (3).
321 - 324.
ISSN 1053-2498
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Abstract
We report a case of fatal central nervous system infection with Scedosporium apiospermum (Pseudallescheria boydii) in a heart transplant recipient. This ubiquitous fungus is known to cause mycetoma and localized infections in patients with otherwise normal conditions. Disseminated infections occur rarely and are seen primarily in patients who are receiving immunosuppressive medications or who have neutropenia. Often life-threatening when infection is disseminated and involves the central nervous system, this diagnosis is difficult to make rapidly because S. apiospermum (P. boydii) mimics Aspergillus spp. and Fusarium spp., both clinically and histopathologically. Imidazoles such as miconazole, but not amphotericin B, are considered the therapeutic compounds of choice. Improved diagnostic and treatment options are needed to optimize management of infections with S. apiospermum (P. boydii).
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Item Type: |
Article
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Status: |
Published |
Creators/Authors: |
Creators | Email | Pitt Username | ORCID  |
---|
Lopez, FA | | | | Crowley, Rebecca S | | | | Wastila, L | | | | Valantine, HA | | | | Remington, JS | | | |
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Date: |
March 1998 |
Date Type: |
Publication |
Journal or Publication Title: |
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation |
Volume: |
17 |
Number: |
3 |
Page Range: |
321 - 324 |
Schools and Programs: |
School of Medicine > Biomedical Informatics |
Refereed: |
Yes |
ISSN: |
1053-2498 |
Article Type: |
Research Article |
MeSH Headings: |
Adult; Brain Diseases--microbiology; Central Nervous System Diseases--microbiology; Fatal Outcome; Heart Transplantation; Humans; Male; Mycetoma--diagnosis; Mycetoma--microbiology; Postoperative Complications; Pseudallescheria--isolation & purification |
PubMed ID: |
9563611 |
Date Deposited: |
29 Aug 2012 21:02 |
Last Modified: |
01 Nov 2017 14:03 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/13835 |
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