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Relationship of body fat and cardiorespiratory fitness with cardiovascular risk in Chinese children

Wang, PG and Gong, J and Wang, SQ and Talbott, EO and Zhang, B and He, QQ (2011) Relationship of body fat and cardiorespiratory fitness with cardiovascular risk in Chinese children. PLoS ONE, 6 (11).

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Abstract

Backgrounds/Objectives: Cardiorespiratory fitness (CRF) and body fat play an important role in elevated risk for cardiovascular disease (CVD). However, the combined effects of CRF and obesity on metabolic health in Chinese children are unclear. The purpose of this study was to investigate the independent and combined associations between body fat, CRF, and CVD risk in Chinese schoolchildren. Methods: The study subjects comprised 676 schoolchildren (392 boys and 284 girls, aged 9.6±0.7 yrs old) in Wuhan, China. Their body mass index (BMI), waist circumference (WC), CRF, blood pressure (BP), lipids, glucose, and pubertal status were assessed. Children were categorized into different groups based on their BMI, WC, and CRF using Chinese obesity cut-off points and CRF sex-specific median points. Metabolic Risk Score (MRS) was computed based on the standardized scores of BP, lipids, and glucose. Results: Multiple linear regression models showed that, in the separate models, body fat was positively associated with MRS while CRF was inversely associated with MRS (p<0.001). However, when assessed simultaneously, only body fat had a significant association with MRS (p<0.001). In general, low-fit children had a lower MRS compared to their counterparts, and a significant difference between the two extreme groups was observed (low CRF and high fat vs. high CRF and low fat, p<0.001). Conclusions: These findings suggest that both body fat and CRF should be considered when interpreting CVD risk in Chinese children, while body fat may be correlated with CVD risk more than CRF. © 2011 Wang et al.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Wang, PG
Gong, J
Wang, SQ
Talbott, EOeot1@pitt.eduEOT1
Zhang, B
He, QQ
Contributors:
ContributionContributors NameEmailPitt UsernameORCID
EditorMohamed Noor, AbdisalanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Date: 16 November 2011
Date Type: Publication
Journal or Publication Title: PLoS ONE
Volume: 6
Number: 11
DOI or Unique Handle: 10.1371/journal.pone.0027896
Refereed: Yes
MeSH Headings: Adipose Tissue--pathology; Blood Glucose--metabolism; Blood Pressure; Body Composition; Body Mass Index; Cardiovascular Diseases--etiology; Cardiovascular Diseases--pathology; Cardiovascular Physiological Phenomena; Child; China; Cross-Sectional Studies; Female; Humans; Lipids--analysis; Male; Obesity--complications; Oxygen Consumption; Physical Endurance--physiology; Respiratory Physiological Phenomena; Risk Factors; Waist Circumference
Other ID: NLM PMC3218065
PubMed Central ID: PMC3218065
PubMed ID: 22114722
Date Deposited: 07 Sep 2012 19:57
Last Modified: 25 Jun 2018 13:57
URI: http://d-scholarship.pitt.edu/id/eprint/13996

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