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Dysfunctional Elimination Syndrome: Is It Related to Urinary Tract Infection or Vesicoureteral Reflux Diagnosed Early in Life?

Shaikh, N and Hoberman, A and Wise, B and Kurs-Lasky, M and Kearney, D and Naylor, S and Haralam, MA and Colborn, DK and Docimo, SG (2003) Dysfunctional Elimination Syndrome: Is It Related to Urinary Tract Infection or Vesicoureteral Reflux Diagnosed Early in Life? Pediatrics, 112 (5). 1134 - 1137. ISSN 0031-4005

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Objective. It has been suggested that urinary tract infections (UTIs) early in life predispose to dysfunctional elimination syndrome (DES). This study evaluated the relationship between early UTI, vesicoureteral reflux (VUR), and DES by comparing two cohorts of school-aged children. Methods. The UTI cohort (n = 123) included children previously enrolled in a prospective treatment trial conducted between 1992 and 1997. All were diagnosed with a febrile UTI before 2 years of age. The comparison cohort (n = 125) included children who were evaluated for fever in the emergency department between 1992 and 1997, whose urine culture was negative. Dysfunctional elimination symptoms were compared in the two cohorts by having families complete a revised version of the Dysfunctional Voiding Scoring System. Results. Completed questionnaires were received from 248 children. There were no significant differences in selected demographic or clinical characteristics between the two cohorts. DES was present in 22% and 21% of children with and without a history of early UTI, respectively. Among children with UTIs, 18% of those with VUR and 25% of those without VUR had DES. Conclusions. Dysfunctional elimination is common in a general pediatric population. Neither UTI nor VUR diagnosed before 2 years of age was associated with DES in school-aged children.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Shaikh, Nnas67@pitt.eduNAS67
Hoberman, A
Wise, B
Kurs-Lasky, M
Kearney, D
Naylor, S
Haralam, MA
Colborn, DK
Docimo, SG
Date: 1 November 2003
Date Type: Publication
Journal or Publication Title: Pediatrics
Volume: 112
Number: 5
Page Range: 1134 - 1137
DOI or Unique Handle: 10.1542/peds.112.5.1134
Schools and Programs: School of Medicine > Pediatrics
Refereed: Yes
ISSN: 0031-4005
MeSH Headings: Child; Child, Preschool; Cohort Studies; Elimination Disorders--etiology; Female; Humans; Male; Prevalence; Questionnaires; Sampling Studies; Urinary Tract Infections--complications; Vesico-Ureteral Reflux--complications; Vulnerable Populations
PubMed ID: 14595058
Date Deposited: 11 Sep 2012 21:27
Last Modified: 02 Feb 2019 16:56


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