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PREFER study: A randomized clinical trial testing treatment preference and two dietary options in behavioral weight management - Rationale, design and baseline characteristics

Burke, LE and Choo, J and Music, E and Warziski, M and Styn, MA and Kim, Y and Sevick, MA (2006) PREFER study: A randomized clinical trial testing treatment preference and two dietary options in behavioral weight management - Rationale, design and baseline characteristics. Contemporary Clinical Trials, 27 (1). 34 - 48. ISSN 1551-7144

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Abstract

Background: Obesity, a disorder associated with a myriad of comorbidities, is increasing at an alarming rate around the world. Given that pharmacotherapy has limited available options and that bariatric surgery is reserved for those who are morbidly obese or who have significant comorbidities, the most common approach to the treatment of obesity is standard behavioral treatment. This approach includes behavior modification related to eating and activity habits. The purpose of this paper is to describe the rationale, design, methods and baseline sample characteristics of a randomized controlled trial of a behavioral intervention in weight loss management, referred to as the PREFER study. Methods: The PREFER study, using a four-group design, includes: (1) a randomization scheme that permits participants to indicate a preferred dietary treatment approach, and (2) two dietary options, one of which is a lacto-ovo-vegetarian diet that has demonstrated potential for long-term adherence. The intervention (32 treatment sessions) is delivered over 12 months and is followed by a 6-month maintenance phase; final assessment occurs at 18 months. Results: We screened 932 individuals and randomized 197 to the study: Treatment Preference-Yes (n = 84) and Treatment Preference-No (n = 98). To maintain a balance across the four treatment groups, 15 subjects who preferred the standard diet had to be discarded from the Treatment Preference-Yes group. Retention at 18 months for the first of three cohorts was 82%. Conclusions: The PREFER study is a single center study and is the first randomized controlled trial examining a lacto-ovo-vegetarian diet as part of weight loss treatment. The ethnically diverse sample includes males and females with a body mass index of 27 to 43. The study has the potential to make a contribution to understanding the role of treatment preference and the potential of a lacto-ovo-vegetarian diet for long-term weight loss. © 2005 Elsevier Inc. All rights reserved.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Burke, LElbu100@pitt.eduLBU100
Choo, J
Music, E
Warziski, M
Styn, MA
Kim, Y
Sevick, MA
Date: 1 February 2006
Date Type: Publication
Journal or Publication Title: Contemporary Clinical Trials
Volume: 27
Number: 1
Page Range: 34 - 48
DOI or Unique Handle: 10.1016/j.cct.2005.08.002
Schools and Programs: School of Nursing > Nursing
Refereed: Yes
ISSN: 1551-7144
MeSH Headings: Adult; Diet, Reducing--psychology; Diet, Vegetarian--psychology; Female; Humans; Male; Middle Aged; Obesity--diet therapy; Patient Compliance; Patient Dropouts; Patient Satisfaction; Reproducibility of Results; Selection Bias; Socioeconomic Factors
PubMed ID: 16233990
Date Deposited: 18 Sep 2012 15:20
Last Modified: 03 Feb 2019 02:55
URI: http://d-scholarship.pitt.edu/id/eprint/14191

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