Burke, LE and Hudson, AG and Warziski, MT and Styn, MA and Music, E and Elci, OU and Sereika, SM
(2007)
Effects of a vegetarian diet and treatment preference on biochemical and dietary variables in overweight and obese adults: A randomized clinical trial.
American Journal of Clinical Nutrition, 86 (3).
588 - 596.
ISSN 0002-9165
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Abstract
Background: A vegetarian diet may lead to numerous health benefits, including weight loss. Objective: We examined the joint effects of personal preference of dietary treatment and a calorie-restricted, low-fat lactoovovegetarian diet (LOV-D) compared with a standard calorie-restricted, low-fat omnivorous diet (STD-D) on changes in weight, total cholesterol, ratio of LDL to HDL cholesterol (LDL:HDL cholesterol), triacylglycerols, insulin resistance, and macronutrient intake during an 18-mo study. Design: This was a randomized clinical trial of 176 overweight and obese adults who were recruited and randomly assigned first to 1 of 2 preference conditions (yes or no). If assigned to Preference-No, they were randomly assigned to 1 of the 2 diet conditions (STD-D or LOV-D). If assigned to Preference-Yes, they were assigned to the diet they indicated as preferred at screening. The 12-mo intervention was followed by a 6-mo maintenance phase. Results: Participants were mainly women (86.9%) and white (70.5%); 75% completed the 18-mo study. A significant interaction between preference and dietary treatment was not observed for any of the outcome variables. However, participants in the Preference-No groups significantly decreased their triacylglycerols (P = 0.04). The only effect observed for diet was a borderline significant decrease in LDL:HDL cholesterol for the LOV-D group (P = 0.06). Within the LOV-D groups, those who were 100% adherent to the LOV-D had significant and marginally significant reductions in monounsaturated fat (P = 0.02) and total fat (P = 0.05) intakes at 18 mo. Conclusions: Our findings suggest that neither prescribing a vegetarian diet nor allowing persons to choose their preferred diet had a significant effect on outcome measures. However, all participants had a significant reduction in total energy and fat intakes and an increase in energy expenditure, which was reflected in reduced body weight. This clinical trial was registered at www.clinicaltrials.gov as NCT00330629. © 2007 American Society for Nutrition.
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Details
| Item Type: |
Article
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| Status: |
Published |
| Creators/Authors: |
|
| Date: |
1 September 2007 |
| Date Type: |
Publication |
| Journal or Publication Title: |
American Journal of Clinical Nutrition |
| Volume: |
86 |
| Number: |
3 |
| Page Range: |
588 - 596 |
| DOI or Unique Handle: |
10.1093/ajcn/86.3.588 |
| Schools and Programs: |
School of Nursing > Nursing |
| Refereed: |
Yes |
| ISSN: |
0002-9165 |
| MeSH Headings: |
Adult; Blood Chemical Analysis; Body Mass Index; Cholesterol--blood; Cholesterol, HDL--blood; Cholesterol, LDL--blood; Diet, Fat-Restricted; Diet, Reducing; Diet, Vegetarian; Exercise--physiology; Female; Follow-Up Studies; Food Preferences; Humans; Insulin Resistance; Male; Middle Aged; Obesity--blood; Obesity--diet therapy; Overweight--blood; Overweight--diet therapy; Patient Compliance; Time Factors; Treatment Outcome; Triglycerides--blood |
| PubMed ID: |
17823421 |
| Date Deposited: |
18 Sep 2012 15:05 |
| Last Modified: |
26 Jan 2022 12:55 |
| URI: |
http://d-scholarship.pitt.edu/id/eprint/14209 |
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