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Maternal age and oral clefts: A reappraisal

Vieira, AR and Orioli, IM and Murray, JC (2002) Maternal age and oral clefts: A reappraisal. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, 94 (5). 530 - 535. ISSN 1079-2104

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Objective. The aim of the study was to test the hypothesis that increased maternal age is associated with a higher risk of having a child with oral clefts. Study design. A meta-analysis of 8 population-based studies with information regarding live birth and oral clefts was performed. Results. No association between increased maternal age and isolated oral clefts was found. Conclusion. Oral clefts occurrence is not correlated with increasing maternal age, and inclusion of data mixing isolated and syndromic cases can confound the analysis and must be avoided. © 2002, Mosby, Inc.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Vieira, ARarv11@pitt.eduARV11
Orioli, IM
Murray, JC
Date: 1 January 2002
Date Type: Publication
Journal or Publication Title: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
Volume: 94
Number: 5
Page Range: 530 - 535
DOI or Unique Handle: 10.1067/moe.2002.128875
Schools and Programs: School of Dental Medicine > Dental Science
Refereed: Yes
ISSN: 1079-2104
MeSH Headings: Adult; Australia--epidemiology; Cleft Lip--epidemiology; Cleft Palate--epidemiology; Confounding Factors (Epidemiology); England--epidemiology; Female; Humans; Hungary--epidemiology; Infant, Newborn; Maternal Age; Netherlands--epidemiology; Odds Ratio; Russia--epidemiology; United States--epidemiology
PubMed ID: 12424443
Date Deposited: 18 Sep 2012 15:02
Last Modified: 28 Feb 2021 04:55


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