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A randomized clinical trial testing treatment preference and two dietary options in behavioral weight management: Preliminary results of the impact of diet at 6 months - PREFER Study

Burke, LE and Styn, MA and Steenkiste, AR and Music, E and Warziski, M and Choo, J (2006) A randomized clinical trial testing treatment preference and two dietary options in behavioral weight management: Preliminary results of the impact of diet at 6 months - PREFER Study. Obesity, 14 (11). 2007 - 2017. ISSN 1930-7381

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Objective: The PREFER study objectives were to examine potential differences in weight loss during a standard behavioral intervention between subjects assigned to one of two calorie- and fat-restricted diets [standard behavior treatment (SBT) and lacto-ovo-vegetarian ([SBT+LOV)], with or without regard to their preferred dietary treatment. This article reports the differences in outcomes between diet groups after the first 6 months of the intervention. Research Methods and Procedures: The study used a four-group design. Subjects (n = 182) were randomized to a treatment preference group and then to a dietary treatment group. For this report, preference groups were combined to permit comparisons by dietary treatment only (SBT, n = 98; SBT+LOV, n = 84). Additional analyses compared SBT+LOV subjects who were 100% adherent (did not consume any meat, fish, or poultry, n = 47) to those who were <100% adherent (n = 24). Results: Significant differences were seen in the baseline to 6-month change scores between the two groups for carbohydrate consumption (p = 0.013), protein consumption (p < 0.001), polyunsaturated-to-saturated fat ratio (p = 0.009), and low-density lipoprotein-cholesterol (LDL-C) level (p = 0.013). Among SBT+LOV subjects, those who were 100% adherent experienced greater reductions in weight (p < 0.001), total cholesterol (p = 0.026), LDL-C (p = 0.034), and glucose (p = 0.002) and consumed less fat (p = 0.030) compared with those who were <100% adherent. Discussion: Differences between dietary treatment groups at 6 months were minimal, most likely because one-third of the SBT+LOV group did not follow the vegetarian diet and because both groups had the same calorie and fat restrictions. SBT+LOV subjects who were 100% adherent were more successful at both weight loss and cholesterol reduction than those who were <100% adherent, suggesting that vegetarian diets are efficacious for weight and cholesterol control. Copyright © 2006 NAASO.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Burke, LElbu100@pitt.eduLBU1000000-0003-2434-9867
Styn, MA
Steenkiste, AR
Music, E
Warziski, M
Choo, J
Date: 1 January 2006
Date Type: Publication
Journal or Publication Title: Obesity
Volume: 14
Number: 11
Page Range: 2007 - 2017
DOI or Unique Handle: 10.1038/oby.2006.235
Schools and Programs: School of Nursing > Nursing
Refereed: Yes
ISSN: 1930-7381
MeSH Headings: Adult; Behavior Therapy; Cholesterol--blood; Diet, Reducing--psychology; Diet, Vegetarian--psychology; Female; Food Preferences; Humans; Hypercholesterolemia--blood; Hypercholesterolemia--diet therapy; Male; Middle Aged; Obesity--blood; Obesity--therapy; Patient Compliance; Time Factors; Treatment Outcome
PubMed ID: 17135618
Date Deposited: 18 Sep 2012 14:33
Last Modified: 26 Jan 2022 12:55


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