The FaceBase Consortium: A comprehensive program to facilitate craniofacial research

Hochheiser, Harry and Aronow, Bruce J and Artinger, Kristin and Beaty, Terri H and Brinkley, James F and Chai, Yang and Fraser, Scott E and Hallgrimsson, Benedikt and Iwata, Junichi and Klein, Ophir and Marazita, Mary L and Murray, Jeffrey C and Murray, Stephen and Pardo-Manuel de Villena, Fernando and Postlethwait, John and Potter, Steven and Shapiro, Linda and Spritz, Richard and Visel, Axel and Weinberg, Seth M and Trainor, Paul A (2012) The FaceBase Consortium: A comprehensive program to facilitate craniofacial research. Developmental Biology, 355 (2). 175 - 182.

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Official URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC344030...

Abstract

The FaceBase Consortium consists of ten interlinked research and technology projects whose goal is to generate craniofacial research data and technology for use by the research community through a central data management and integrated bioinformatics hub. Funded by the National Institute of Dental and Craniofacial Research (NIDCR) and currently focused on studying the development of the middle region of the face, the Consortium will produce comprehensive datasets of global gene expression patterns, regulatory elements and sequencing; will generate anatomical and molecular atlases; will provide human normative facial data and other phenotypes; conduct follow up studies of a completed genome-wide association study; generate independent data on the genetics of craniofacial development, build repositories of animal models and of human samples and data for community access and analysis; and will develop software tools and animal models for analyzing and functionally testing and integrating these data. The FaceBase website (http://www.facebase.org) will serve as a web home for these efforts, providing interactive tools for exploring these datasets, together with discussion forums and other services to support and foster collaboration within the craniofacial research community.

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Creators	Email	Pitt Username	ORCID
Hochheiser, Harry	harryh@pitt.edu	HARRYH	0000-0001-8793-9982
Aronow, Bruce J
Artinger, Kristin
Beaty, Terri H
Brinkley, James F
Chai, Yang
Fraser, Scott E
Hallgrimsson, Benedikt
Iwata, Junichi
Klein, Ophir
Marazita, Mary L	marazita@pitt.edu	MARAZITA
Murray, Jeffrey C
Murray, Stephen
Pardo-Manuel de Villena, Fernando
Postlethwait, John
Potter, Steven
Shapiro, Linda
Spritz, Richard
Visel, Axel
Weinberg, Seth M	smwst46@pitt.edu	SMWST46
Trainor, Paul A