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A randomized clinical trial of a standard versus vegetarian diet for weight loss: The impact of treatment preference

Burke, LE and Warziski, M and Styn, MA and Music, E and Hudson, AG and Sereika, SM (2008) A randomized clinical trial of a standard versus vegetarian diet for weight loss: The impact of treatment preference. International Journal of Obesity, 32 (1). 166 - 176. ISSN 0307-0565

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Background: With obesity rampant, methods to achieve sustained weight loss remain elusive. Objective: To compare the long-term weight-loss efficacy of 2 cal and fat-restricted diets, standard (omnivorous) versus lacto-ovo-vegetarian, and to determine the effect of a chosen diet versus an assigned diet. Design, subjects: A randomized clinical trial was conducted with 176 adults who were sedentary and overweight (mean body mass index, 34.0 kg/m2). Participants were first randomly assigned to either receive their preferred diet or be assigned to a diet group and second, were given their diet of preference or randomly assigned to a standard weight-loss diet or a lacto-ovo-vegetarian diet. Participants underwent a university-based weight-control program consisting of daily dietary and exercise goals plus 12 months of behavioral counseling followed by a 6-month maintenance phase. Measurements: Percentage change in body weight, body mass index, waist circumference, low- and high-density lipoprotein, glucose, insulin and macronutrient intake. Results: The program was completed by 132 (75%) of the participants. At 18 months, mean percentage weight loss was greater (P=0.01) in the two groups that were assigned a diet (standard, 8.0% (s.d., 7.8%); vegetarian, 7.9% (s.d., 8.1%)) than in those provided the diet of their choice (standard, 3.9% (s.d., 6.1%); vegetarian, 5.3% (s.d., 6.2%)). No difference was observed in weight loss between the two types of diet. Over the 18-month program, all groups showed significant weight loss. Conclusions: Participants assigned to their dietary preference did not have enhanced treatment outcomes. However, all groups lost weight with losses ranging from 4 to 8% at 18 months. © 2008 Nature Publishing Group All rights reserved.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Burke, LElbu100@pitt.eduLBU1000000-0003-2434-9867
Warziski, M
Styn, MA
Music, E
Hudson, AG
Sereika, SMssereika@pitt.eduSSEREIKA
Date: 12 January 2008
Date Type: Publication
Journal or Publication Title: International Journal of Obesity
Volume: 32
Number: 1
Page Range: 166 - 176
DOI or Unique Handle: 10.1038/sj.ijo.0803706
Schools and Programs: School of Nursing > Nursing
Refereed: Yes
ISSN: 0307-0565
MeSH Headings: Abdomen--anatomy & histology; Adolescent; Adult; Body Mass Index; Body Weight--physiology; Cholesterol--blood; Diet, Fat-Restricted; Diet, Reducing; Diet, Vegetarian; Humans; Middle Aged; Overweight--blood; Overweight--diet therapy; Triglycerides--blood; Weight Loss--physiology
PubMed ID: 17700579
Date Deposited: 20 Sep 2012 20:45
Last Modified: 26 Jan 2022 12:55


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