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Longitudinal relationship between physical activity and cardiometabolic factors in overweight and obese adults

Choo, J and Elci, OU and Yang, K and Turk, MW and Styn, MA and Sereika, SM and Music, E and Burke, LE (2010) Longitudinal relationship between physical activity and cardiometabolic factors in overweight and obese adults. European Journal of Applied Physiology, 108 (2). 329 - 336. ISSN 1439-6319

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Few studies have reported longitudinal relationships between physical activity (PA) and cardiometabolic risk factors over time using repeated assessments in overweight or obese adults. We conducted a longitudinal study in 127 participants (81% with body mass index > 30 kg/m2) who completed a 12-month behavioral intervention for weight loss between 2003 and 2005 in Pittsburgh, PA, USA. Using absolute change scores from baseline to each time point (i.e., 6 and 12 months) for all studied variables (Δ = time point - baseline), we performed mixed effects modeling to examine relationships between PA and cardiometabolic risk factors, after adjusting for body weight, energy intake and other covariates (i.e., age, gender, and ethnicity). PA was assessed as energy expenditure (kcal/week) using the Paffenbarger activity questionnaire. Over the 12-month period, energy expenditure increased (Δ1,370 kcal/week at 6 months vs. Δ886 kcal/week at 12 months); body weight decreased (Δ8.9 kg at 6 months vs. Δ8.4 kg at 12 months). The average increase in energy expenditure over 12 months was significantly and independently related to reductions in total cholesterol (F = 6.25, p = 0.013), low-density lipoprotein cholesterol (LDL-C) (F = 5.08, p = 0.025) and fasting blood glucose (F = 5.10, p = 0.025), but not to other risk factors (i.e., fasting insulin, high-density lipoprotein cholesterol, triglycerides, and waist circumference). In conclusion, among overweight and obese adults undergoing a weight loss intervention, increased energy expenditure over 12 months may improve total cholesterol and LDL-C, important coronary risk factors, and fasting blood glucose, a metabolic risk factor. © 2009 Springer-Verlag.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Choo, J
Elci, OU
Yang, K
Turk, MW
Styn, MA
Sereika, SMssereika@pitt.eduSSEREIKA
Music, E
Burke, LElbu100@pitt.eduLBU1000000-0003-2434-9867
Date: 1 January 2010
Date Type: Publication
Journal or Publication Title: European Journal of Applied Physiology
Volume: 108
Number: 2
Page Range: 329 - 336
DOI or Unique Handle: 10.1007/s00421-009-1203-6
Schools and Programs: School of Nursing > Nursing
Refereed: Yes
ISSN: 1439-6319
MeSH Headings: Adult; Body Mass Index; Cholesterol, HDL--blood; Cholesterol, LDL--blood; Energy Metabolism--physiology; Exercise--physiology; Female; Humans; Male; Middle Aged; Obesity--metabolism; Overweight--metabolism; Risk Factors; Triglycerides--blood; Weight Loss
Other ID: NLM NIHMS351952, NLM PMC3319046
PubMed Central ID: PMC3319046
PubMed ID: 19806358
Date Deposited: 20 Sep 2012 20:41
Last Modified: 26 Jan 2022 12:55


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