Taioli, E and Ragin, C and Robertson, L and Linkov, F and Thurman, NE and Vieira, AR
(2010)
Cleft lip and palate in family members of cancer survivors.
Cancer Investigation, 28 (9).
958 - 962.
ISSN 0735-7907
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Abstract
The presence of cleft lip with or without cleft palate (CL/P) in family members of cancer patients was investigated. An epidemiological questionnaire including family history of cancer and congenital oral cleft malformations was administered to 168 cancer survivors and a population-based sample of 170 healthy subjects. In the control group, 1.2% reported a family member with CL/P; among cancer survivors the figure was 4.2% (odds ratio: 3.7; 95% confidence interval: 0.75-17.8; p = .07). Among cancer survivors with a family member with CL/P, there was an apparent excess of testicular cancer and melanoma in comparison with the cancer survivors with no family history of CL/P. These preliminary results suggest a common etiologic background for cancer and CL/P. © 2010 Informa Healthcare USA, Inc.
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Details
Item Type: |
Article
|
Status: |
Published |
Creators/Authors: |
Creators | Email | Pitt Username | ORCID  |
---|
Taioli, E | | | | Ragin, C | | | | Robertson, L | | | | Linkov, F | | | | Thurman, NE | | | | Vieira, AR | arv11@pitt.edu | ARV11 | |
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Date: |
1 October 2010 |
Date Type: |
Publication |
Journal or Publication Title: |
Cancer Investigation |
Volume: |
28 |
Number: |
9 |
Page Range: |
958 - 962 |
DOI or Unique Handle: |
10.3109/07357907.2010.483510 |
Schools and Programs: |
School of Dental Medicine > Dental Science |
Refereed: |
Yes |
ISSN: |
0735-7907 |
MeSH Headings: |
Adult; Aged; Cleft Lip--epidemiology; Cleft Palate--epidemiology; Comorbidity; Family; Family Health; Female; Humans; Male; Melanoma--epidemiology; Middle Aged; Neoplasms--epidemiology; Pennsylvania--epidemiology; Questionnaires; Survivors--statistics & numerical data; Testicular Neoplasms--epidemiology; Young Adult |
PubMed ID: |
20569073 |
Date Deposited: |
20 Sep 2012 19:41 |
Last Modified: |
20 Feb 2020 13:55 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/14336 |
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