Link to the University of Pittsburgh Homepage
Link to the University Library System Homepage Link to the Contact Us Form

Cleft lip and palate in family members of cancer survivors

Taioli, E and Ragin, C and Robertson, L and Linkov, F and Thurman, NE and Vieira, AR (2010) Cleft lip and palate in family members of cancer survivors. Cancer Investigation, 28 (9). 958 - 962. ISSN 0735-7907

[img] Plain Text (licence)
Available under License : See the attached license file.

Download (1kB)


The presence of cleft lip with or without cleft palate (CL/P) in family members of cancer patients was investigated. An epidemiological questionnaire including family history of cancer and congenital oral cleft malformations was administered to 168 cancer survivors and a population-based sample of 170 healthy subjects. In the control group, 1.2% reported a family member with CL/P; among cancer survivors the figure was 4.2% (odds ratio: 3.7; 95% confidence interval: 0.75-17.8; p = .07). Among cancer survivors with a family member with CL/P, there was an apparent excess of testicular cancer and melanoma in comparison with the cancer survivors with no family history of CL/P. These preliminary results suggest a common etiologic background for cancer and CL/P. © 2010 Informa Healthcare USA, Inc.


Social Networking:
Share |


Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Taioli, E
Ragin, C
Robertson, L
Linkov, F
Thurman, NE
Vieira, ARarv11@pitt.eduARV11
Date: 1 October 2010
Date Type: Publication
Journal or Publication Title: Cancer Investigation
Volume: 28
Number: 9
Page Range: 958 - 962
DOI or Unique Handle: 10.3109/07357907.2010.483510
Schools and Programs: School of Dental Medicine > Dental Science
Refereed: Yes
ISSN: 0735-7907
MeSH Headings: Adult; Aged; Cleft Lip--epidemiology; Cleft Palate--epidemiology; Comorbidity; Family; Family Health; Female; Humans; Male; Melanoma--epidemiology; Middle Aged; Neoplasms--epidemiology; Pennsylvania--epidemiology; Questionnaires; Survivors--statistics & numerical data; Testicular Neoplasms--epidemiology; Young Adult
PubMed ID: 20569073
Date Deposited: 20 Sep 2012 19:41
Last Modified: 20 Feb 2020 13:55


Monthly Views for the past 3 years

Plum Analytics

Actions (login required)

View Item View Item