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Inflammation, coagulation and cardiovascular disease in HIV-infected individuals

Duprez, DA and Neuhaus, J and Kuller, LH and Tracy, R and Belloso, W and De Wit, S and Drummond, F and Lane, HC and Ledergerber, B and Lundgren, J and Nixon, D and Paton, NI and Prineas, RJ and Neaton, JD (2012) Inflammation, coagulation and cardiovascular disease in HIV-infected individuals. PLoS ONE, 7 (9).

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Abstract

Background: The SMART study was a trial of intermittent use of antiretroviral therapy (ART) (drug conservation [DC]) versus continuous use of ART (viral suppression [VS]) as a strategy to reduce toxicities, including cardiovascular disease (CVD) risk. We studied the predictive value of high sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6) and D-dimer with CVD morbidity and mortality in HIV-infected patients who were enrolled in SMART beyond other measured CVD risk factors.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Duprez, DA
Neuhaus, J
Kuller, LHKullerL@edc.pitt.eduKULLER
Tracy, R
Belloso, W
De Wit, S
Drummond, F
Lane, HC
Ledergerber, B
Lundgren, J
Nixon, D
Paton, NI
Prineas, RJ
Neaton, JD
Contributors:
ContributionContributors NameEmailPitt UsernameORCID
EditorThorne, ClaireUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Date: 10 September 2012
Date Type: Publication
Journal or Publication Title: PLoS ONE
Volume: 7
Number: 9
DOI or Unique Handle: 10.1371/journal.pone.0044454
Schools and Programs: Graduate School of Public Health > Epidemiology
Refereed: Yes
Other ID: NLM PMC3438173
PubMed Central ID: PMC3438173
PubMed ID: 22970224
Date Deposited: 19 Oct 2012 21:21
Last Modified: 30 Mar 2021 12:55
URI: http://d-scholarship.pitt.edu/id/eprint/15900

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