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Augmenting Transport versus Increasing Cold Storage to Improve Vaccine Supply Chains

Haidari, LA and Connor, DL and Wateska, AR and Brown, ST and Mueller, LE and Norman, BA and Schmitz, MM and Paul, P and Rajgopal, J and Welling, JS and Leonard, J and Chen, SI and Lee, BY (2013) Augmenting Transport versus Increasing Cold Storage to Improve Vaccine Supply Chains. Master Essay, University of Pittsburgh.

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Background:When addressing the urgent task of improving vaccine supply chains, especially to accommodate the introduction of new vaccines, there is often a heavy emphasis on stationary storage. Currently, donations to vaccine supply chains occur largely in the form of storage equipment.Methods:This study utilized a HERMES-generated detailed, dynamic, discrete event simulation model of the Niger vaccine supply chain to compare the impacts on vaccine availability of adding stationary cold storage versus transport capacity at different levels and to determine whether adding stationary storage capacity alone would be enough to relieve potential bottlenecks when pneumococcal and rotavirus vaccines are introduced by 2015.Results:Relieving regional level storage bottlenecks increased vaccine availability (by 4%) more than relieving storage bottlenecks at the district (1% increase), central (no change), and clinic (no change) levels alone. Increasing transport frequency (or capacity) yielded far greater gains (e.g., 15% increase in vaccine availability when doubling transport frequency to the district level and 18% when tripling). In fact, relieving all stationary storage constraints could only increase vaccine availability by 11%, whereas doubling the transport frequency throughout the system led to a 26% increase and tripling the frequency led to a 30% increase. Increasing transport frequency also reduced the amount of stationary storage space needed in the supply chain. The supply chain required an additional 61,269L of storage to relieve constraints with the current transport frequency, 55,255L with transport frequency doubled, and 51,791L with transport frequency tripled.Conclusions:When evaluating vaccine supply chains, it is important to understand the interplay between stationary storage and transport. The HERMES-generated dynamic simulation model showed how augmenting transport can result in greater gains than only augmenting stationary storage and can reduce stationary storage needs. © 2013 Haidari et al.


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Item Type: Other Thesis, Dissertation, or Long Paper (Master Essay)
Status: Published
CreatorsEmailPitt UsernameORCID
Haidari, LA
Connor, DL
Wateska, AR
Brown, ST
Mueller, LE
Norman, BAbanorman@pitt.eduBANORMAN
Schmitz, MM
Paul, P
Rajgopal, Jj.rajgopal@pitt.eduGUNNER10000-0001-7730-8749
Welling, JS
Leonard, J
Chen, SI
Lee, BY
ContributionContributors NameEmailPitt UsernameORCID
Committee ChairVoohrees, Ronaldrev12@pitt.eduREV12UNSPECIFIED
Committee MemberMartinson, Jeremyjmartins@pitt.eduJMARTINSUNSPECIFIED
Date: 22 May 2013
Date Type: Publication
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Journal or Publication Title: PLoS ONE
Volume: 8
Number: 5
DOI or Unique Handle: 10.1371/journal.pone.0064303
Institution: University of Pittsburgh
Schools and Programs: Graduate School of Public Health > Epidemiology
Thesis Type: Master Essay
Refereed: No
Date Deposited: 08 Feb 2013 14:58
Last Modified: 28 Jan 2021 19:55


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