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United States Acculturation and Cancer Patients' End-of-Life Care

Wright, AA and Stieglitz, H and Kupersztoch, YM and Paulk, ME and Kim, Y and Katz, IT and Munoz, F and Jimenez, RB and Mutchler, J and Rivera, L and Back, AL and Prigerson, HG (2013) United States Acculturation and Cancer Patients' End-of-Life Care. PLoS ONE, 8 (3).

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Background: Culture shapes how people understand illness and death, but few studies examine whether acculturation influences patients' end-of-life treatment preferences and medical care. Methods and Findings: In this multi-site, prospective, longitudinal cohort study of terminally-ill cancer patients and their caregivers (n = 171 dyads), trained interviewers administered the United States Acculturation Scale (USAS). The USAS is a 19-item scale developed to assess the degree of "Americanization" in first generation or non-US born caregivers of terminally-ill cancer patients. We evaluated the internal consistency, concurrent, criterion, and content validity of the USAS. We also examined whether caregivers' USAS scores predicted patients' communication, treatment preferences, and end-of-life medical care in multivariable models that corrected for significant confounding influences (e.g. education, country of origin, English proficiency). The USAS measure was internally consistent (Cronbach α = 0.98); and significantly associated with US birthplace (r = 0.66, P<0.0001). USAS scores were predictive of patients' preferences for prognostic information (AOR = 1.31, 95% CI:1.00-1.72), but not comfort asking physicians' questions about care (AOR 1.23, 95% CI:0.87-1.73). They predicted patients' preferences for feeding tubes (AOR = 0.68, 95% CI:0.49-0.99) and wish to avoid dying in an intensive care unit (AOR = 1.36, 95% CI:1.05-1.76). Scores indicating greater acculturation were also associated with increased odds of patient participation in clinical trials (AOR = 2.20, 95% CI:1.28-3.78), compared with lower USAS scores, and greater odds of patients receiving chemotherapy (AOR = 1.59, 95% CI:1.20-2.12). Conclusion: The USAS is a reliable and valid measure of "Americanization" associated with advanced cancer patients' end-of-life preferences and care. USAS scores indicating greater caregiver acculturation were associated with increased odds of patient participation in cancer treatment (chemotherapy, clinical trials) compared with lower scores. Future studies should examine the effects of acculturation on end-of-life care to identify patient and provider factors that explain these effects and targets for future interventions to improve care (e.g., by designing more culturally-competent health education materials). © 2013 Wright et al.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Wright, AA
Stieglitz, H
Kupersztoch, YM
Paulk, ME
Kim, Y
Katz, IT
Munoz, F
Jimenez, RB
Mutchler, J
Rivera, L
Back, AL
Prigerson, HG
Date: 11 March 2013
Date Type: Publication
Journal or Publication Title: PLoS ONE
Volume: 8
Number: 3
DOI or Unique Handle: 10.1371/journal.pone.0058663
Schools and Programs: School of Public Health > Biostatistics
School of Medicine > Medicine
School of Nursing > Nursing
Refereed: Yes
Date Deposited: 08 Apr 2013 17:15
Last Modified: 25 Jan 2019 21:55


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