Cao, L and MacIejewski, JP and Elzner, S and Amantini, D and Wipf, P
(2012)
Synthesis of 1,2,4-triazines and the triazinoisoquinolinedione DEF ring system of noelaquinone.
Organic and Biomolecular Chemistry, 10 (30).
5811 - 5814.
ISSN 1477-0520
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Abstract
The intramolecular Staudinger-aza-Wittig reaction is used for a general synthesis of 1,2,5,6-tetrahydro-1,2,4-triazines, a structural motif reported for the natural product noelaquinone. The DEF moiety of noelaquinone was obtained in 13 steps and 2% overall yield, and the structure of the synthetic product was confirmed by X-ray analysis. © 2012 The Royal Society of Chemistry.
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Details
| Item Type: |
Article
|
| Status: |
Published |
| Creators/Authors: |
|
| Date: |
14 August 2012 |
| Date Type: |
Publication |
| Journal or Publication Title: |
Organic and Biomolecular Chemistry |
| Volume: |
10 |
| Number: |
30 |
| Page Range: |
5811 - 5814 |
| DOI or Unique Handle: |
10.1039/c2ob25353d |
| Schools and Programs: |
Dietrich School of Arts and Sciences > Chemistry |
| Refereed: |
Yes |
| ISSN: |
1477-0520 |
| MeSH Headings: |
Biological Agents--chemistry; Chemistry Techniques, Synthetic; Heterocyclic Compounds with 4 or More Rings--chemistry; Isoquinolines--chemical synthesis; Isoquinolines--chemistry; Triazines--chemical synthesis; Triazines--chemistry |
| Other ID: |
NLM NIHMS371302 [Available on 08/14/13], NLM PMC3535313 [Available on 08/14/13] |
| PubMed Central ID: |
PMC3535313 |
| PubMed ID: |
22473572 |
| Date Deposited: |
28 May 2013 15:14 |
| Last Modified: |
02 Feb 2019 15:56 |
| URI: |
http://d-scholarship.pitt.edu/id/eprint/18730 |
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