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A new fluorous methoxymethyl (<sup>F</sup>MOM) protecting group for alcohols

Curran, DP and Ogoe, C (2006) A new fluorous methoxymethyl (<sup>F</sup>MOM) protecting group for alcohols. QSAR and Combinatorial Science, 25 (8-9). 732 - 735. ISSN 1611-020X

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A new fluorous analogue of the popular MOM (methoxymethyl) protecting group can be introduced by reactions of alcohols with 1H,1H,2H,2H,3H,3H- perfluoroundecyloxymethyl chloride (C8F17(CH 2)3OCH2Cl) and the resulting fluorous methoxymethyl (FMOM) adducts can be deprotected under Brønsted or Lewis acidic conditions. The results suggest that the FMOM protecting group will find use in a number of fluorous synthesis settings. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Curran, DPcurran@pitt.eduCURRAN
Ogoe, C
Date: 1 September 2006
Date Type: Publication
Journal or Publication Title: QSAR and Combinatorial Science
Volume: 25
Number: 8-9
Page Range: 732 - 735
DOI or Unique Handle: 10.1002/qsar.200640047
Schools and Programs: Dietrich School of Arts and Sciences > Chemistry
Refereed: Yes
ISSN: 1611-020X
Date Deposited: 07 Jun 2013 20:32
Last Modified: 22 Jun 2021 12:56


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