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A microwave assisted intramolecular-furan-Diels-Alder approach to 4-substituted indoles

Petronijevic, F and Timmons, C and Cuzzupe, A and Wipf, P (2009) A microwave assisted intramolecular-furan-Diels-Alder approach to 4-substituted indoles. Chemical Communications (1). 104 - 106. ISSN 1359-7345

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The key steps of a versatile new protocol for the convergent synthesis of 3,4-disubstituted indoles are the addition of an α-lithiated alkylaminofuran to a carbonyl compound, a microwave-accelerated intramolecular Diels-Alder cycloaddition and an in situ double aromatization reaction. © The Royal Society of Chemistry.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Petronijevic, F
Timmons, C
Cuzzupe, A
Wipf, Ppwipf@pitt.eduPWIPF
Date: 1 January 2009
Date Type: Publication
Journal or Publication Title: Chemical Communications
Number: 1
Page Range: 104 - 106
DOI or Unique Handle: 10.1039/b816989f
Schools and Programs: Dietrich School of Arts and Sciences > Chemistry
Refereed: Yes
ISSN: 1359-7345
MeSH Headings: Cyclization; Electrons; Furans--chemistry; Heterocyclic Compounds--chemistry; Indicators and Reagents; Indoles--chemical synthesis; Indoles--radiation effects; Lithium--chemistry; Microwaves
Other ID: NLM NIHMS140546, NLM PMC2736609
PubMed Central ID: PMC2736609
PubMed ID: 19082013
Date Deposited: 03 Jul 2013 14:56
Last Modified: 02 Feb 2019 15:57


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