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Total synthesis of luotonin and a small library of AB-ring substituted analogues by cascade radical annulation of isonitriles

Tangirala, R and Antony, S and Agama, K and Pommier, Y and Curran, DP (2005) Total synthesis of luotonin and a small library of AB-ring substituted analogues by cascade radical annulation of isonitriles. Synlett (18). 2843 - 2846. ISSN 0936-5214

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Abstract

A four-step total synthesis of luotonin is deployed to make a small library of AB-ring substituted analogues. These analogues show weak activity in a standard topoisomerase I mediated DNA cleavage assay. © Georg Thieme Verlag Stuttgart.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Tangirala, R
Antony, S
Agama, K
Pommier, Y
Curran, DPcurran@pitt.eduCURRAN
Date: 3 November 2005
Date Type: Publication
Journal or Publication Title: Synlett
Number: 18
Page Range: 2843 - 2846
DOI or Unique Handle: 10.1055/s-2005-918923
Schools and Programs: Dietrich School of Arts and Sciences > Chemistry
Refereed: Yes
ISSN: 0936-5214
Date Deposited: 15 Jul 2013 19:54
Last Modified: 02 Feb 2019 15:59
URI: http://d-scholarship.pitt.edu/id/eprint/19279

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