Ring-closing metathesis approach to dictyostatin

Kangani, CO and Brückner, AM and Curran, DP (2005) Ring-closing metathesis approach to dictyostatin. Organic Letters, 7 (3). 379 - 382. ISSN 1523-7060

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Abstract

(Chemical Equation Presented) An esterification/ring-closing metathesis approach to dictyostatin and discodermolide is introduced. The approach provides for facile fragment coupling of two main segments of these natural products at the C10-C11 alkene with high to complete Z-selectivity.

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Details

Item Type:	Article
Status:	Published
Creators/Authors:	Creators Email Pitt Username ORCID Kangani, CO Brückner, AM Curran, DP curran@pitt.edu CURRAN
Date:	3 February 2005
Date Type:	Publication
Journal or Publication Title:	Organic Letters
Volume:	7
Number:	3
Page Range:	379 - 382
DOI or Unique Handle:	10.1021/ol0478279
Schools and Programs:	Dietrich School of Arts and Sciences > Chemistry
Refereed:	Yes
ISSN:	1523-7060
MeSH Headings:	Alkanes--chemistry; Carbamates--chemistry; Esters--chemistry; Indicators and Reagents; Lactones--chemistry; Macrolides--chemical synthesis; Molecular Conformation; Oxidation-Reduction; Pyrones--chemistry; Structure-Activity Relationship
PubMed ID:	15673244
Date Deposited:	07 Aug 2013 14:48
Last Modified:	15 Oct 2017 06:55
URI:	http://d-scholarship.pitt.edu/id/eprint/19531

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