Radical cyclization approach to spirocyclohexadienones

González-López De Turiso, F and Curran, DP (2005) Radical cyclization approach to spirocyclohexadienones. Organic Letters, 7 (1). 151 - 154. ISSN 1523-7060

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Abstract

(Chemical Equation Presented) Cyclization of an aryl radical at the ipso position of a p-O-aryl-substituted acetamide or benzamide generates oxindoles or quinolones bearing spirocyclohexadienone rings. This versatile reaction is applied to formal syntheses of the vasopressin inhibitor SR121463A and aza-galanthamine.

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Details

Item Type:	Article
Status:	Published
Creators/Authors:	Creators Email Pitt Username ORCID González-López De Turiso, F Curran, DP curran@pitt.edu CURRAN
Date:	6 January 2005
Date Type:	Publication
Journal or Publication Title:	Organic Letters
Volume:	7
Number:	1
Page Range:	151 - 154
DOI or Unique Handle:	10.1021/ol0477226
Schools and Programs:	Dietrich School of Arts and Sciences > Chemistry
Refereed:	Yes
ISSN:	1523-7060
MeSH Headings:	Cyclization; Cyclohexanes--chemistry; Cyclohexenes; Spiro Compounds--chemistry
PubMed ID:	15625000
Date Deposited:	07 Aug 2013 15:09
Last Modified:	02 Feb 2019 15:58
URI:	http://d-scholarship.pitt.edu/id/eprint/19542

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