Curran, DP and Amatore, M and Guthrie, D and Campbell, M and Go, E and Luo, Z
(2003)
Synthesis and reactions of fluorous carbobenzyloxy (<sup>f</sup>Cbz) derivatives of α-amino acids.
Journal of Organic Chemistry, 68 (12).
4643 - 4647.
ISSN 0022-3263
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Abstract
Fluorous carbobenzyloxy (FCbz) reagents RfCH2CH2C6H4CH2 OC(O)OSu (where Su is succinimidoyl and Rf is C6F13 and C8F17) have been used to make FCbz derivatives of 18 of the 20 natural amino acids. The potential utility of this new family of reagents in both standard fluorous synthesis with spe separation and fluorous quasiracemic synthesis is illustrated with representative reactions of the FCbz-Phe derivatives.
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Details
Item Type: |
Article
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Status: |
Published |
Creators/Authors: |
Creators | Email | Pitt Username | ORCID  |
---|
Curran, DP | curran@pitt.edu | CURRAN | | Amatore, M | | | | Guthrie, D | | | | Campbell, M | | | | Go, E | | | | Luo, Z | | | |
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Date: |
13 June 2003 |
Date Type: |
Publication |
Journal or Publication Title: |
Journal of Organic Chemistry |
Volume: |
68 |
Number: |
12 |
Page Range: |
4643 - 4647 |
DOI or Unique Handle: |
10.1021/jo0344283 |
Schools and Programs: |
Dietrich School of Arts and Sciences > Chemistry |
Refereed: |
Yes |
ISSN: |
0022-3263 |
MeSH Headings: |
Amino Acids--chemistry; Benzene Derivatives--chemical synthesis; Benzene Derivatives--chemistry; Catalysis; Chromatography, High Pressure Liquid; Fluorides--chemical synthesis; Fluorides--chemistry; Indicators and Reagents; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism |
PubMed ID: |
12790566 |
Date Deposited: |
30 Jan 2014 17:01 |
Last Modified: |
22 Jun 2021 12:56 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/20428 |
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