Link to the University of Pittsburgh Homepage
Link to the University Library System Homepage Link to the Contact Us Form

Microwave Heating Effects Rapid and Selective Decarboalkoxylation of Mono-Alkylated Malonates and β-Ketoesters

Curran, DP and Zhang, Q (2003) Microwave Heating Effects Rapid and Selective Decarboalkoxylation of Mono-Alkylated Malonates and β-Ketoesters. Advanced Synthesis and Catalysis, 345 (3). 329 - 332. ISSN 1615-4150

[img] Plain Text (licence)
Available under License : See the attached license file.

Download (1kB)

Abstract

Brief microwave irradiation of mono-alkylated malonates and β-ketoesters at 160-200 °C in wet DMF induces smooth and selective decarboalkoxylation. Observations suggest that this reaction occurs by nucleophilic attack of water at the ester carbonyl carbon (hydrolysis) followed by decarboxylation of the resulting acid. The process occurs despite the absence of traditional acid, base or nucleophile catalysts or reagents.


Share

Citation/Export:
Social Networking:
Share |

Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Curran, DPcurran@pitt.eduCURRAN
Zhang, Q
Date: 1 March 2003
Date Type: Publication
Journal or Publication Title: Advanced Synthesis and Catalysis
Volume: 345
Number: 3
Page Range: 329 - 332
DOI or Unique Handle: 10.1002/adsc.200390033
Schools and Programs: Dietrich School of Arts and Sciences > Chemistry
Refereed: Yes
ISSN: 1615-4150
Date Deposited: 07 Feb 2014 00:00
Last Modified: 02 Feb 2019 15:58
URI: http://d-scholarship.pitt.edu/id/eprint/20460

Metrics

Monthly Views for the past 3 years

Plum Analytics

Altmetric.com


Actions (login required)

View Item View Item