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Synthesis of functionalized oxazolines and oxazoles with DAST and deoxo-fluor

Phillips, AJ and Uto, Y and Wipf, P and Reno, MJ and Williams, DR (2000) Synthesis of functionalized oxazolines and oxazoles with DAST and deoxo-fluor. Organic Letters, 2 (8). 1165 - 1168. ISSN 1523-7060

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A mild and highly efficient cyclization of β-hydroxy amides to oxazolines is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from β-hydroxy amides is also presented.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Phillips, AJ
Uto, Y
Wipf, Ppwipf@pitt.eduPWIPF
Reno, MJ
Williams, DR
Date: 20 April 2000
Date Type: Publication
Journal or Publication Title: Organic Letters
Volume: 2
Number: 8
Page Range: 1165 - 1168
DOI or Unique Handle: 10.1021/ol005777b
Schools and Programs: Dietrich School of Arts and Sciences > Chemistry
Refereed: Yes
ISSN: 1523-7060
MeSH Headings: Diethylamines--chemistry; Fluorine--chemistry; Indicators and Reagents--chemistry; Oxazoles--chemical synthesis
PubMed ID: 10804580
Date Deposited: 21 Feb 2014 21:08
Last Modified: 02 Feb 2019 16:56


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