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Cadmium and liver disease

Chen, Yi (2014) Cadmium and liver disease. Master Essay, University of Pittsburgh.

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Cadmium, which released into the environment, has increased in past 100 years. Exposure to cadmium induced harmful environmental effects in the atomsphere and biosphere, contributes to adverse health effects in humans, including liver damages. Liver disease is one of top 10 causes of death around all the world, which mostly reduces the quality of life and longevity for humans. It is important to understand the relationship between liver disease and cadmium exposure in order to improve public health. This literature review consults research articles, peer reviews, government reports and regulations to determine the public health importance regarding cadmium-related liver disease. It is clear that chronic cadmium exposure is related with some kinds of liver diseases, both in animals and humans. Although cadmium is classified as a carcinogenic agent, there is insufficient evidence to support that liver cancer is associated with cadmium exposure. Further studies are required to investigate whether chronic low-doses of cadmium exposure could induce liver cancer and other liver diseases. If environmental exposure to cadmium is ultimately found to cause liver diseases, further efforts should be made to reduce it. For example, the government could consider developing regulations for cadmium in agriculture products and tobacco products. Additionally, clinical trial could be initiated to evaluate therapeutic agents to mitigate toxic exposure to cadmium.


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Item Type: Other Thesis, Dissertation, or Long Paper (Master Essay)
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Chen, Yi
ContributionContributors NameEmailPitt UsernameORCID
Committee ChairPeterson, Jamesjimmpy@pitt.eduJIMMPYUNSPECIFIED
Committee MemberHolguin, Fernandoholguinf@upmc.eduUNSPECIFIEDUNSPECIFIED
Date: 25 April 2014
Date Type: Publication
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Publisher: University of Pittsburgh
Institution: University of Pittsburgh
Schools and Programs: School of Public Health > Environmental and Occupational Health
Degree: MPH - Master of Public Health
Thesis Type: Master Essay
Refereed: Yes
Date Deposited: 21 May 2015 14:19
Last Modified: 20 Dec 2018 00:55


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