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Balouris, Sondra A. (2014) DEVELOPMENT AND VALIDATION OF THE CEREBRAL PERFORMANCE CATEGORIES-EXTENDED (CPC-E). Doctoral Dissertation, University of Pittsburgh. (Unpublished)

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Optimizing resuscitation efforts post sudden cardiac arrest (CA) and improving mortality have received a great deal of attention while efforts to measure and understand functional outcomes post CA have not been adequately addressed. The Cerebral Performance Category (CPC) is considered the “gold” standard outcome measurement tool after CA yet it lacks psychometric validation. The purpose of this project was to develop and establish the psychometric properties of the revised CPC: the CPC-Extended (CPC-E). The specific aims were to establish the CPC-E’s content validity, and to test its reliability, and feasibility in the hospital setting. We established content validity by identifying existing Domains in the CPC and adding additional Domains to be included in the CPC-E by conducting a systematic review of the literature, and by engaging a panel of CA and Rehabilitation experts. We identified 10 Domains to be included in the CPC-E: Alert, Logical Thinking, Attention, Short-Term Memory, Motor, Basic Activities of Daily Living (BADL), Mood, Fatigue, Complex Activities of Daily Living (CADL), and Return to Work (RTW). We tested the CPC-E’s intra-rater reliability (IR) percent agreement (n = 30; range = 73.3% - 100%) and inter-rater reliability (IRR) (n = 50; range = 60% - 100%) using retrospective chart reviews of the electronic medical records, and its feasibility in a “live” hospital setting (n = 11; range = 90.9% - 100%). For both IR and IRR chart reviews, ICC scores could not be calculated for Mood, Fatigue and CADL Domains due to lack of variance in the data. For both IR and IRR chart reviews, 5/10 Domains had large amounts of missing data while Mood, Fatigue and CADL Domains had missing data 100% of the time. In contrast, no data were missing for the IRR-Hospital for any of the 10 Domains. We established and developed content validity for each of these unique domains and demonstrated the CPC-E’s excellent reliability via “live” administration, in contrast to retrospective medical chart reviews. The CPC-E yields more efficient, reliable and meaningful ratings.


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Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Balouris, Sondra A.sab992@pitt.eduSAB992
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee CoChairRaina, Ketki Dhruvkraina@pitt.eduKRAINA
Committee CoChairHolm, Margo Bmbholm@pitt.eduMBHOLM
Committee MemberBertolet, Marniemhb12@pitt.eduMHB12
Committee MemberCallaway, Cliftoncallawaycw@upmc.eduCALLAWAY
Committee MemberRittenberger,
Committee MemberRogers, Joan Cjcr@pitt.eduJCR
Date: 23 May 2014
Date Type: Publication
Defense Date: 9 April 2014
Approval Date: 23 May 2014
Submission Date: 16 April 2014
Access Restriction: 5 year -- Restrict access to University of Pittsburgh for a period of 5 years.
Number of Pages: 174
Institution: University of Pittsburgh
Schools and Programs: School of Health and Rehabilitation Sciences > Rehabilitation Science
Degree: PhD - Doctor of Philosophy
Thesis Type: Doctoral Dissertation
Refereed: Yes
Uncontrolled Keywords: A screening and outcome tool post cardiac arrest.
Date Deposited: 23 May 2014 15:02
Last Modified: 23 May 2019 05:15


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