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Pharmaceuticals in the water: histological effects and intersex wildlife and sexual disruption

Watson, Katie (2014) Pharmaceuticals in the water: histological effects and intersex wildlife and sexual disruption. Master Essay, University of Pittsburgh.

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Abstract

Pharmaceuticals can cause serious hazardous effects on the aquatic environment. Humans that are being treated with the drugs often excrete the hazardous pharmaceuticals that are of interest in this paper. Wastewater treatment plants are unable to completely remove the pharmaceuticals from the water and thus the fish downstream of the sewage effluents are the most likely to be affected. The following steroid estrogens and non-steroidal anti-inflammatory drugs (NSAIDs) have serious effects on wild fish: 17β-estradiol, estrone, and 17α-ethinylestradiol, and diclofenac. The steroid estrogen pharmaceuticals have been proven to cause sexual disruption in a variety of wild fish including: roach fish, white suckers, and zebra fish. The NSAIDs have been proven to cause major histological effects that lead to organ failure in other wild fish species, including the rainbow trout. The public health importance of studying these hazardous pharmaceutical and their effects on the ecosystem is necessary to determine long-term effects and potential hazardous effects to humans.


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Details

Item Type: Other Thesis, Dissertation, or Long Paper (Master Essay)
Status: Unpublished
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Watson, Katie
Contributors:
ContributionContributors NameEmailPitt UsernameORCID
Committee ChairPitt, Brucebrucep@pitt.eduBRUCEPUNSPECIFIED
Committee MemberTerry, Martha Annmaterry@pitt.eduMATERRYUNSPECIFIED
Date: April 2014
Date Type: Publication
Defense Date: 24 April 2014
Submission Date: 25 April 2014
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Publisher: University of Pittsburgh
Institution: University of Pittsburgh
Schools and Programs: Graduate School of Public Health > Environmental and Occupational Health
Degree: MPH - Master of Public Health
Thesis Type: Master Essay
Refereed: Yes
Uncontrolled Keywords: Pharmaceuticals, Intersex, fish, Feminization
Date Deposited: 26 May 2015 19:49
Last Modified: 02 Feb 2021 11:55
URI: http://d-scholarship.pitt.edu/id/eprint/21489

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