Isoflavones in soy-based infant formulas and effects on thyroid function

Guo, Rui (2014) Isoflavones in soy-based infant formulas and effects on thyroid function. Master Essay, University of Pittsburgh.

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Abstract

Soy-based infant formulas have been available for nearly one hundred years and more than 20 million American infants have been fed soy-based infant formulas since the 1970s. Currently, soy-based infant formulas account for approximately 25 percent of the formulas marketed in the United States. Although the present recommendations for soy-based infant formulas used in the United States are likely still valid, the public health significance of the safety of soy-based infant formulas receives a great deal of attention. Infants fed with soy-based infant formulas are exposed to substantial levels of soy isoflavones, which are phytoestrogens with potential hormonal activity due to their chemical similarity to endogenous estrogen. Isoflavones possess weak estrogenic activity and could theoretically negatively affect endocrine development. This has led researchers to study the health effects of isoflavones in soy-based infant formulas on thyroid functions. This literature review discusses previous animal and human studies and provides suggestions for further studies in the research of isoflavones in soy-based infant formulas and effects on thyroid function.

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Details

Item Type:	Other Thesis, Dissertation, or Long Paper (Master Essay)
Status:	Unpublished
Creators/Authors:	Creators Email Pitt Username ORCID Guo, Rui
Contributors:	Contribution Contributors Name Email Pitt Username ORCID Committee Chair Peterson, James jimmyp@pitt.edu JIMMYP UNSPECIFIED Committee Member Bodnar, Lisa bodnar@edc.pitt.edu LBODNAR UNSPECIFIED
Date:	April 2014
Date Type:	Publication
Access Restriction:	No restriction; Release the ETD for access worldwide immediately.
Publisher:	University of Pittsburgh
Institution:	University of Pittsburgh
Schools and Programs:	School of Public Health > Environmental and Occupational Health
Degree:	MPH - Master of Public Health
Thesis Type:	Master Essay
Refereed:	Yes
Date Deposited:	26 May 2015 17:57
Last Modified:	30 Mar 2022 11:56
URI:	http://d-scholarship.pitt.edu/id/eprint/21491

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