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Summary of the IADR Cariology Research, Craniofacial Biology, and Mineralized Tissue Groups Symposium, Iguaçu Falls, Brazil, June 2012: Gene-environment Interactions and Epigenetics in Oral Diseases: Enamel Formation and its Clinical Impact on Tooth Defects, Caries, and Erosion.

Modesto, Adriana and Klein, Ophir and Tenuta, Livia MA and Gerlach, Raquel F and Vieira, Alexandre R (2013) Summary of the IADR Cariology Research, Craniofacial Biology, and Mineralized Tissue Groups Symposium, Iguaçu Falls, Brazil, June 2012: Gene-environment Interactions and Epigenetics in Oral Diseases: Enamel Formation and its Clinical Impact on Tooth Defects, Caries, and Erosion. Dent 3000, 1 (1). ISSN 2167-8677

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Abstract

Characteristics of enamel may influence or modulate individual susceptibility to caries and erosion. These characteristics are defined during development, which is under strict genetic control, but can easily be modified in many ways by environmental factors. In the symposium, translational aspects of embryology, biochemistry, and genetics of amelogenesis were presented. The symposium provided unique insight into how basic sciences integrate with clinically relevant problems. The need for improved understanding of risks at the individual level, taking into consideration both environmental exposures and genetic background, was presented. The symposium was divided into four stepwise and interconnected topics as follows: 1) The Many Faces of Enamel Development; 2) Enamel Pathogenesis: Biochemistry Lessons; 3) Environmental Factors on Enamel Formation; and, 4) Genetic Variation in Enamel Formation Genes.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Modesto, Adriana
Klein, Ophir
Tenuta, Livia MA
Gerlach, Raquel F
Vieira, Alexandre Ralexandre_vieira@pitt.eduARV11
Date: 2013
Date Type: Publication
Journal or Publication Title: Dent 3000
Volume: 1
Number: 1
Schools and Programs: School of Dental Medicine > Dental Science
Refereed: Yes
ISSN: 2167-8677
Funders: NIDCR NIH HHS (R01 DE018914)
Date Deposited: 30 Jun 2014 18:36
Last Modified: 30 Oct 2018 14:00
URI: http://d-scholarship.pitt.edu/id/eprint/22078

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