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Synthesis of an 8-pentafluorosulfanyl analog of the antimalarial agent mefloquine

Mo, T and Mi, X and Milner, EE and Dow, GS and Wipf, P (2010) Synthesis of an 8-pentafluorosulfanyl analog of the antimalarial agent mefloquine. Tetrahedron Letters, 51 (39). 5137 - 5140. ISSN 0040-4039

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Abstract

The 8-SF5 analog of mefloquine was synthesized in nine steps from commercially available starting materials and in five steps from a novel ortho-SF5-substituted aniline intermediate. © 2010 Elsevier Ltd. All rights reserved.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Mo, T
Mi, X
Milner, EE
Dow, GS
Wipf, Ppwipf@pitt.eduPWIPF
Date: 29 September 2010
Date Type: Publication
Journal or Publication Title: Tetrahedron Letters
Volume: 51
Number: 39
Page Range: 5137 - 5140
DOI or Unique Handle: 10.1016/j.tetlet.2010.07.113
Schools and Programs: Dietrich School of Arts and Sciences > Chemistry
Refereed: Yes
ISSN: 0040-4039
Date Deposited: 18 Jul 2014 21:19
Last Modified: 22 Jun 2021 12:55
URI: http://d-scholarship.pitt.edu/id/eprint/22225

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