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Seroprevalence of hepatitis C and B in southern Africa

Tamele Mahumane, Arlete (2014) Seroprevalence of hepatitis C and B in southern Africa. Master Essay, University of Pittsburgh.

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Abstract

Background: More than 130 million people are chronically infected with hepatitis C virus (HCV) worldwide. After infection, the virus chronically infects 55-85% of infected individuals; only 15-45% are able to clear out the virus within 6 months. The prevalence of HCV in Southern Africa is not well established. The World Health Organization (WHO) estimates a combined HCV seroprevalence of 2.0-2.5% for Southern and East Africa. My objective is to characterize the prevalence of HCV and HBV in Southern African, by performing a literature review. A section on Human immunodeficiency virus (HIV) co-infection was included in the review. HCV and HBV have public health importance since they share the same route of transmission as HIV. Results: The prevalence of HCV in Southern Africa varies according to region with a range of 0.8-6.8%, and HBV prevalence is similar in all countries, with prevalence above 8%. Most studies reported higher prevalence of HCV among HIV-infected individual, as compared to non HIV-infected individuals. The transmission of HCV is Southern African countries occur mainly through unsafe therapeutic injections and unscreened blood transfusion. Conclusions: The HCV prevalence in Southern Africa is low. More rigorous population based studies are needed to more accurately assess prevalence of HCV and HBV in Southern Africa.


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Details

Item Type: Other Thesis, Dissertation, or Long Paper (Master Essay)
Status: Unpublished
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Tamele Mahumane, Arlete
Contributors:
ContributionContributors NameEmailPitt UsernameORCID
Committee ChairHarrison, Lee Hlharriso@edc.pitt.eduLHARRISOUNSPECIFIED
Committee MemberBrooks, Maria M.mbrooks@pitt.eduMBROOKSUNSPECIFIED
Committee MemberMcMahon, Deborahmcmahond@pitt.eduMCMAHONDUNSPECIFIED
Date: 2014
Date Type: Publication
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Publisher: University of Pittsburgh
Institution: University of Pittsburgh
Schools and Programs: Graduate School of Public Health > Epidemiology
Degree: MD - Doctor of Medicine
Thesis Type: Master Essay
Refereed: Yes
Date Deposited: 13 Aug 2015 22:37
Last Modified: 03 Dec 2021 12:55
URI: http://d-scholarship.pitt.edu/id/eprint/22654

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