Lee, BY and Connor, DL and Kitchen, SB and Bacon, KM and Shah, M and Brown, ST and Bailey, RR and Laosiritaworn, Y and Burke, DS and Cummings, DAT
(2011)
Economic value of dengue vaccine in Thailand.
American Journal of Tropical Medicine and Hygiene, 84 (5).
764 - 772.
ISSN 0002-9637
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Abstract
With several candidate dengue vaccines under development, this is an important time to help stakeholders (e.g., policy makers, scientists, clinicians, and manufacturers) better understand the potential economic value (cost-effectiveness) of a dengue vaccine, especially while vaccine characteristics and strategies might be readily altered. We developed a decision analytic Markov simulation model to evaluate the potential health and economic value of administering a dengue vaccine to an individual (≤ 1 year of age) in Thailand from the societal perspective. Sensitivity analyses evaluated the effects of ranging various vaccine (e.g., cost, efficacy, side effect), epidemiological (dengue risk), and disease (treatment-seeking behavior) characteristics. A ≥ 50% efficacious vaccine was highly cost-effective [< 1x per capita gross domestic product (GDP) ($4,289)] up to a total vaccination cost of $60 and cost-effective [< 3x per capita GDP ($12,868)] up to a total vaccination cost of $200. When the total vaccine series was $1.50, many scenarios were cost saving. Copyright © 2011 by The American Society of Tropical Medicine and Hygiene.
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Details
Item Type: |
Article
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Status: |
Published |
Creators/Authors: |
Creators | Email | Pitt Username | ORCID  |
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Lee, BY | byl1@pitt.edu | BYL1 | | Connor, DL | | | | Kitchen, SB | | | | Bacon, KM | | | | Shah, M | | | | Brown, ST | | | | Bailey, RR | | | | Laosiritaworn, Y | | | | Burke, DS | donburke@pitt.edu | DONBURKE | | Cummings, DAT | | | |
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Centers: |
Other Centers, Institutes, Offices, or Units > Center for Vaccine Research |
Date: |
1 May 2011 |
Date Type: |
Publication |
Journal or Publication Title: |
American Journal of Tropical Medicine and Hygiene |
Volume: |
84 |
Number: |
5 |
Page Range: |
764 - 772 |
DOI or Unique Handle: |
10.4269/ajtmh.2011.10-0624 |
Schools and Programs: |
Graduate School of Public Health > Biostatistics Graduate School of Public Health > Epidemiology School of Medicine > Biomedical Informatics School of Medicine > Medicine |
Refereed: |
Yes |
ISSN: |
0002-9637 |
Date Deposited: |
07 May 2015 19:26 |
Last Modified: |
02 Feb 2019 16:57 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/24409 |
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