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The impact of a physical geographic barrier on the dynamics of measles

Vora, A and Burke, DS and Cummings, DAT (2008) The impact of a physical geographic barrier on the dynamics of measles. Epidemiology and Infection, 136 (5). 713 - 720. ISSN 0950-2688

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Spatial-temporal patterns of measles incidence reflect the spatial distribution of human hosts. The heterogeneous spatial distribution of communities has been shown to introduce spatially dependent temporal lags in the timing of measles incidence. Incidence patterns reflect internal dynamics within a community and coupling of communities through the movement of infectious individuals. The central role of human movement in coupling dynamics in separate communities suggests that physical geographic barriers to movement should reduce spatial-temporal correlation. We examine measles dynamics in Maryland and Pennsylvania during the period of 1917-1938. The central feature of interest is the Chesapeake Bay, which separates Maryland into two distinct regions. We find that correlation of measles incidences in communities separated by the bay is reduced compared to communities not separated by the bay, suggesting the bay acted as a barrier to human movement during this time sufficient to decouple measles dynamics in Maryland counties. © 2007 Cambridge University Press.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Vora, A
Burke, DSdonburke@pitt.eduDONBURKE
Cummings, DAT
Centers: Other Centers, Institutes, Offices, or Units > Center for Vaccine Research
Date: 1 April 2008
Date Type: Publication
Journal or Publication Title: Epidemiology and Infection
Volume: 136
Number: 5
Page Range: 713 - 720
DOI or Unique Handle: 10.1017/s0950268807009193
Schools and Programs: Graduate School of Public Health > Epidemiology
Refereed: Yes
ISSN: 0950-2688
Date Deposited: 07 May 2015 19:05
Last Modified: 02 Feb 2019 16:57


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