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NCI workshop report: Clinical and computational requirements for correlating imaging phenotypes with genomics signatures

Colen, R and Foster, I and Gatenby, R and Giger, ME and Gillies, R and Gutman, D and Heller, M and Jain, R and Madabhushi, A and Madhavan, S and Napel, S and Rao, A and Saltz, J and Tatum, J and Verhaak, R and Whitman, G and Zhang, Y (2014) NCI workshop report: Clinical and computational requirements for correlating imaging phenotypes with genomics signatures. Translational Oncology, 7 (5). 556 - 569.

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Abstract

The National Cancer Institute (NCI) Cancer Imaging Program organized two related workshops on June 26-27, 2013, entitled “Correlating Imaging Phenotypes with Genomics Signatures Research” and “Scalable Computational Resources as Required for Imaging-Genomics Decision Support Systems.” The first workshop focused on clinical and scientific requirements, exploring our knowledge of phenotypic characteristics of cancer biological properties to determine whether the field is sufficiently advanced to correlate with imaging phenotypes that underpin genomics and clinical outcomes, and exploring new scientific methods to extract phenotypic features from medical images and relate them to genomics analyses. The second workshop focused on computational methods that explore informatics and computational requirements to extract phenotypic features from medical images and relate them to genomics analyses and improve the accessibility and speed of dissemination of existing NIH resources. These workshops linked clinical and scientific requirements of currently known phenotypic and genotypic cancer biology characteristics with imaging phenotypes that underpin genomics and clinical outcomes. The group generated a set of recommendations to NCI leadership and the research community that encourage and support development of the emerging radiogenomics research field to address short-and longer-term goals in cancer research.

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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Colen, R
Foster, I
Gatenby, R
Giger, ME
Gillies, R
Gutman, D
Heller, M
Jain, R
Madabhushi, A
Madhavan, S
Napel, S
Rao, A
Saltz, J
Tatum, J
Verhaak, R
Whitman, G
Zhang, Y
Date: 1 January 2014
Date Type: Publication
Journal or Publication Title: Translational Oncology
Volume: 7
Number: 5
Page Range: 556 - 569
DOI or Unique Handle: 10.1016/j.tranon.2014.07.007
Schools and Programs: School of Medicine > Radiology
Refereed: Yes
Date Deposited: 09 Apr 2015 14:18
Last Modified: 30 Mar 2021 14:56
URI: http://d-scholarship.pitt.edu/id/eprint/24667

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