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Sleep outcomes in children with single-suture craniosynostosis compared with unaffected controls

Sun, B and Cloonan, YK and Collett, BR and Speltz, ML (2017) Sleep outcomes in children with single-suture craniosynostosis compared with unaffected controls. Master Essay, University of Pittsburgh.

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Objective: To compare risk for sleep-disordered breathing between children with and without single-suture craniosynostosis. Participants: A total of 184 children with single-suture craniosynostosis and 184 controls. Main Outcome Measures: Parent reported sleep-disordered breathing-related symptoms. Results: Current sleep problems were reported in 19% of patients with single-suture craniosynostosis and 14% of controls (adjusted odds ratio = 1.6; 95% CI, 0.9 to 2.8). Ever having sleep problems was reported in 25% and 23% of cases and controls, respectively (adjusted odds ratio = 1.2; 95% CI, 0.7 to 1.9). Overall, snoring was statistically associated with single-suture craniosynostosis (P = .01) and was more often reported as 2- nights per week (versus never) in patients with single-suture craniosynostosis (13%) than in controls (4%) (adjusted odds ratio = 3.5; 95% CI, 1.5 to 8.2). Conclusions: Though preliminary, increased presence of snoring during sleep in children with single-suture craniosynostosis compared with controls suggests that children with isolated single-suture craniosynostosis may be at increased risk for sleep-disordered breathing. Further study using standardized assessments of sleep-disordered breathing is needed.


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Item Type: Other Thesis, Dissertation, or Long Paper (Master Essay)
Status: Published
CreatorsEmailPitt UsernameORCID
Sun, BBAS154@pitt.eduBAS154
Cloonan, YK
Collett, BR
Speltz, ML
ContributionContributors NameEmailPitt UsernameORCID
Committee MemberTepper, Pingcloonany@edc.pitt.eduYKC1UNSPECIFIED
Committee ChairCloonan, Yonatepperp@edc.pitt.eduUNSPECIFIEDUNSPECIFIED
Committee MemberFinegold, Daviddavid.finegold@chp.eduUNSPECIFIEDUNSPECIFIED
Date: 1 November 2017
Date Type: Publication
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Journal or Publication Title: Cleft Palate-Craniofacial Journal
Volume: 54
Number: 6
Page Range: 734 - 738
DOI or Unique Handle: 10.1597/16-090
Institution: University of Pittsburgh
Schools and Programs: School of Public Health > Epidemiology
Thesis Type: Master Essay
Refereed: Yes
ISSN: 1055-6656
Date Deposited: 05 Nov 2015 00:01
Last Modified: 30 Mar 2021 20:55


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