Pomfret, Sarah A
(2016)
Characterizing oropharyngeal swallowing following single lung transplantation in adults.
Undergraduate Thesis, University of Pittsburgh.
(Unpublished)
Abstract
Swallowing is a physiologically complex kinematic process during which abnormal obstruction of bolus flow of incoordination can occur. Dysphagia, or a difficulty with swallowing, is a concern following single-lung transplantation (SLT) due to the high risk of recurrent laryngeal nerve damage, upper airway trauma secondary to orotracheal intubation, disruption of pulmonary sensorimotor circuits responsible for airway penetration, and the required levels of immunosuppression during and following surgery. Post-operatively, repetitive aspiration events are a major contributing factor in the long-term failure of lung allograft function. The goal of this descriptive, retrospective study is to quantitatively describe the characteristics of swallowing kinematic function through six durational measures in a group of 10 patients (age 49-68) following single-lung transplantation, describe airway protection ordinally through penetration-aspiration scale scores, and to compare findings from these patients to published norms for healthy adults. By explicitly describing the swallow physiology of a sample of patients with SLTs, clinically significant risk factors will be identified to help researchers and clinicians consider better treatment and safe swallowing strategies for future patients in order to mitigate adverse post-operative events, effectively increasing the functional lifespan of the transplant organ, and thusly decreasing morbidity and patient mortality.
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Details
| Item Type: |
University of Pittsburgh ETD
|
| Status: |
Unpublished |
| Creators/Authors: |
|
| ETD Committee: |
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| Date: |
25 April 2016 |
| Date Type: |
Publication |
| Defense Date: |
24 March 2016 |
| Approval Date: |
25 April 2016 |
| Submission Date: |
19 April 2016 |
| Access Restriction: |
No restriction; Release the ETD for access worldwide immediately. |
| Number of Pages: |
49 |
| Institution: |
University of Pittsburgh |
| Schools and Programs: |
David C. Frederick Honors College
School of Health and Rehabilitation Sciences > Communication Science and Disorders |
| Degree: |
BPhil - Bachelor of Philosophy |
| Thesis Type: |
Undergraduate Thesis |
| Refereed: |
Yes |
| Uncontrolled Keywords: |
Swallowing, oropharyngeal, dysphagia, aspiration, adults, lung transplantation, videofluoroscopy |
| Date Deposited: |
25 Apr 2016 19:29 |
| Last Modified: |
15 Nov 2016 14:32 |
| URI: |
http://d-scholarship.pitt.edu/id/eprint/27748 |
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