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The association between social support and medication adherence in adults with rheumatoid arthritis

Takedai, Teika (2016) The association between social support and medication adherence in adults with rheumatoid arthritis. Undergraduate Thesis, University of Pittsburgh. (Unpublished)

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The association between social support and medication adherence has been studied in several chronic diseases. However, this association has not been extensively explored in patients with rheumatoid arthritis (RA), especially with valid and objective measures. The purpose of this study was to examine the association between social support and medication adherence in adults with RA using a valid and reliable social support questionnaire, the Interpersonal Support Evaluation List (ISEL), and the Medication Event Monitoring System (MEMS) to objectively measure medication adherence of RA drugs. A cross-sectional, descriptive, correlational design was used for this secondary analysis of data from a randomized controlled trial of a behavioral intervention to improve medication adherence in patients with RA. The parent study used convenience sampling, and a total of 567 subjects were included in this secondary analysis. At baseline, the subjects completed a sociodemographic questionnaire and the ISEL. Then the subjects were instructed to use the MEMS cap for 30 days. Multivariate logistic regression analyses were used to examine which of the four ISEL subscale scores (tangible, appraisal, self-esteem, and belonging) best predicted each of the adherence measures (dose adherence, days adherence, and on-time adherence). No social support subscale significantly predicted days adherence. Tangible social support was a significant predictor of dose adherence (OR=1.082, 95% CI=1.008 - 1.162). For on-time adherence, self-esteem social support was a significant predictor (OR=0.942, 95% CI=0.893 - 0.994). These results may be due to controlling for the effect of other social support subscale measures that may be related to alternate variables affecting the associations between the adherence and social support. A further study examining these variables is recommended for a greater understanding of the role of social support on medication adherence in persons with RA.


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Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Takedai, Teikatet17@pitt.eduTET17
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairSchlenk, Elizabeth
Sereika, Susan
Ehrlich-Jones, Linda
Date: 26 April 2016
Date Type: Publication
Defense Date: 23 March 2016
Approval Date: 26 April 2016
Submission Date: 21 April 2016
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Number of Pages: 33
Institution: University of Pittsburgh
Schools and Programs: David C. Frederick Honors College
School of Nursing > Nursing
Degree: BSN - Bachelor of Science in Nursing
Thesis Type: Undergraduate Thesis
Refereed: Yes
Uncontrolled Keywords: Social support Medication Adherence Rheumatoid arthritis
Date Deposited: 26 Apr 2016 19:32
Last Modified: 15 Nov 2016 14:33


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