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Effectiveness of supportive periodontal therapy on tooth survival among patients with chronic periodontitis

ALOTAIBI, ALANOUD and Vieira, Alexandre R (2016) Effectiveness of supportive periodontal therapy on tooth survival among patients with chronic periodontitis. Master's Thesis, University of Pittsburgh. (Unpublished)

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INTRODUCTION: Prevention of tooth loss and maintaining favorable periodontal status are the ultimate goals of periodontal therapy. The aim of this study was to evaluate the effectiveness of non-surgical periodontal therapy and supportive periodontal care in arresting the progression of chronic periodontitis and in preventing tooth loss.

MATERIALS AND METHODS: Periodontal charts, self-reported medical history, and interleukin-1 (IL-1) polymorphism genotypes of 100 patients were obtained from the University of Pittsburgh School of Dental Medicine Dental Registry and DNA Repository (DRDR) after screening of 4,825 subjects. In our study we have included third molars, teeth lost during active periodontal treatment (APT), and those lost during supportive periodontal care (SPC). We used tooth loss (TL) and clinical attachment loss (CAL) as outcomes of disease affection in our analysis. Fisher’s exact test was used to investigate the association between tooth loss and different risk factors. Paired t-test was conducted to detect the difference in means of CAL between baseline and final periodontal assessments.

RESULTS: There were 59 patients (36 males and 23 females with an average age of 52 years) that lost at least one tooth. Tooth mortality rate declined in patients who attended supportive periodontal program for six years compared to those who received supportive periodontal therapy for one year only (0.52 and 3.4 teeth/patient/year, respectively). Increased risk of tooth loss was found to be associated with diabetes (P=0.01), as well as high blood pressure (P<0.0001). We did not find an association between tooth loss and polymorphisms in interleukin IL-1α/IL-1β (rs1800587, P=0.36 and rs1143634, P=0.51, respectively). During the first year of supportive periodontal treatment, the clinical attachment loss showed a significant reduction (CAL gain of 0.36 mm, P=0.0697). Moreover, a significant increase in CAL was noted in the group of patients who attended regular periodontal maintenance for six years (CAL progression of 0.38mm, P=0.037).

CONCLUSION: Our findings suggested that supportive periodontal therapy is effective for the long-term stability of periodontal disease in high-risk patients in our sample.


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Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Vieira, Alexandre
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Thesis AdvisorVieira, Alexandre
Committee MemberSfeir, Charles csfeir@pitt.ed
Committee MemberWilliams, KellyKellyWilliams@pitt.eduKLB31
Date: 16 May 2016
Date Type: Publication
Defense Date: 27 April 2016
Approval Date: 16 May 2016
Submission Date: 1 May 2016
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Number of Pages: 51
Institution: University of Pittsburgh
Schools and Programs: School of Dental Medicine > Dental Science
Degree: MS - Master of Science
Thesis Type: Master's Thesis
Refereed: Yes
Uncontrolled Keywords: Supportive periodontal therapy, Tooth loss, Chronic periodontitis.
Date Deposited: 16 May 2016 20:42
Last Modified: 15 Nov 2016 14:33


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