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Depression and anxiety disorders among hospitalized women with breast cancer

Vin-Raviv, N and Akinyemiju, TF and Galea, S and Bovbjerg, DH (2015) Depression and anxiety disorders among hospitalized women with breast cancer. PLoS ONE, 10 (6).

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Purpose: To document the prevalence of depression and anxiety disorders, and their associations with mortality among hospitalized breast cancer patients. Methods: We examined the associations between breast cancer diagnosis and the diagnoses of anxiety or depression among 4,164 hospitalized breast cancer cases matched with 4,164 non-breast cancer controls using 2006-2009 inpatient data obtained from the Nationwide Inpatient Sample database. Conditional logistic regression models were used to compute odds ratios (ORs) and 95% confidence intervals (CI) for the associations between breast cancer diagnosis and diagnoses of anxiety or depression. We also used binary logistic regression models to examine the association between diagnoses of depression or anxiety, and in-hospital mortality among breast cancer patients. Results: We observed that breast cancer cases were less likely to have a diagnosis of depression (OR=0.63, 95% CI: 0.52-0.77), and less likely to have a diagnosis of anxiety (OR=0.68, 95% CI: 0.52-0.90) compared with controls. This association remained after controlling for race/ethnicity, residential income, insurance and residential region. Breast cancer patients with a depression diagnosis also had lower mortality (OR=0.69, 95% CI: 0.52-0.89) compared with those without a depression diagnosis, but there was no significant difference in mortality among those with and without anxiety diagnoses. Conclusion: Diagnoses of depression and anxiety in breast cancer patients were less prevalent than expected based on our analysis of hospitalized breast cancer patients and matched nonbreast cancer controls identified in the NIS dataset using ICD-9 diagnostic codes. Results suggest that under-diagnosis of mental health problems may be common among hospitalized women with a primary diagnosis of breast cancer. Future work may fruitfully explore reasons for, and consequences of, inappropriate identification of the mental health needs of breast cancer patients.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Vin-Raviv, N
Akinyemiju, TF
Galea, S
Bovbjerg, DHdhb15@pitt.eduDHB15
ContributionContributors NameEmailPitt UsernameORCID
Centers: Other Centers, Institutes, Offices, or Units > Pittsburgh Cancer Institute
Date: 2 June 2015
Date Type: Publication
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Journal or Publication Title: PLoS ONE
Volume: 10
Number: 6
DOI or Unique Handle: 10.1371/journal.pone.0129169
Institution: University of Pittsburgh
Schools and Programs: Dietrich School of Arts and Sciences > Psychology
School of Public Health > Behavioral and Community Health Sciences
School of Medicine > Psychiatry
Refereed: Yes
Date Deposited: 23 Aug 2016 14:11
Last Modified: 30 Mar 2021 15:55


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