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Hanmer, J and Feeny, D and Fischhoff, B and Hays, RD and Hess, R and Pilkonis, PA and Revicki, DA and Roberts, MS and Tsevat, J and Yu, L (2015) The PROMIS of QALYs. Health and Quality of Life Outcomes, 13 (1).

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Measuring health and health-related quality of life (HRQoL) is important for tracking the health of individuals and populations over time. Generic HRQoL measures allow for comparison across health conditions. One form of generic HRQoL measures are profile measures, which provide a description of health across several different domains (such as physical functioning, depression, and pain). Recent advances in health profile measurement include the development of measures based on item response theory. The Patient-Reported Outcomes Measurement Information System (PROMIS®) has been constructed using this theory. Another form of generic HRQoL measures are utility measures, which assess the value of health states. Multi-attribute utility theory provides a framework for valuing disparate domains of health and aggregating them into a single preference-based score. Such a score provides an overall measure of health outcomes as well as a quality of life weight for use in decision analyses and cost-effectiveness analyses. Developing a utility score for PROMIS® would allow simultaneous estimation of both health profile and utility scores using a single measure. The purpose of this paper is to provide a roadmap of the methodological steps necessary to create such a scoring system.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Hanmer, Jjzh23@pitt.eduJZH23
Feeny, D
Fischhoff, B
Hays, RD
Hess, R
Pilkonis, PApap1@pitt.eduPAP1
Revicki, DA
Roberts, MSmroberts@pitt.eduMROBERTS
Tsevat, J
Yu, L
Date: 11 August 2015
Date Type: Publication
Journal or Publication Title: Health and Quality of Life Outcomes
Volume: 13
Number: 1
DOI or Unique Handle: 10.1186/s12955-015-0321-6
Schools and Programs: Graduate School of Public Health > Health Policy & Management
School of Medicine > Medicine
School of Medicine > Psychiatry
Refereed: Yes
Date Deposited: 17 Aug 2016 13:51
Last Modified: 30 Mar 2021 11:55


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