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Future perspectives in melanoma research. Meeting report from the " Melanoma Bridge. Napoli, December 2nd-4th 2012"

Ascierto, PA and Grimaldi, AM and Acquavella, N and Borgognoni, L and Calabrò, L and Cascinelli, N and Cesano, A and Del Vecchio, M and Eggermont, AM and Faries, M and Ferrone, S and Fox, BA and Gajewski, TF and Galon, J and Gnjatic, S and Gogas, H and Kashani-Sabet, M and Kaufman, HL and Larkin, J and Lo, RS and Mantovani, A and Margolin, K and Melief, C and McArthur, G and Palmieri, G and Puzanov, I and Ribas, A and Seliger, B and Sosman, J and Suenaert, P and Tarhini, AA and Trinchieri, G and Vidal-Vanaclocha, F and Wang, E and Ciliberto, G and Mozzillo, N and Marincola, FM and Thurin, M (2013) Future perspectives in melanoma research. Meeting report from the " Melanoma Bridge. Napoli, December 2nd-4th 2012". Journal of Translational Medicine, 11 (1).

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Abstract

Recent insights into the genetic and somatic aberrations have initiated a new era of rapidly evolving targeted and immune-based treatments for melanoma. After decades of unsuccessful attempts to finding a more effective cure in the treatment of melanoma now we have several drugs active in melanoma. The possibility to use these drugs in combination to improve responses to overcome the resistance, to potentiate the action of immune system with the new immunomodulating antibodies, and identification of biomarkers that can predict the response to a particular therapy represent new concepts and approaches in the clinical management of melanoma. The third " Melanoma Research: " A bridge from Naples to the World" meeting, shortened as " Bridge Melanoma Meeting" took place in Naples, December 2 to 4th, 2012. The four topics of discussion at this meeting were: advances in molecular profiling and novel biomarkers, combination therapies, novel concepts toward integrating biomarkers and therapies into contemporary clinical management of patients with melanoma across the entire spectrum of disease stage, and the knowledge gained from the biology of tumor microenvironment across different tumors as a bridge to impact on prognosis and response to therapy in melanoma. This international congress gathered more than 30 international faculty members who in an interactive atmosphere which stimulated discussion and exchange of their experience regarding the most recent advances in research and clinical management of melanoma patients. © 2013 Ascierto et al.; licensee BioMed Central Ltd.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Ascierto, PA
Grimaldi, AM
Acquavella, N
Borgognoni, L
Calabrò, L
Cascinelli, N
Cesano, A
Del Vecchio, M
Eggermont, AM
Faries, M
Ferrone, S
Fox, BA
Gajewski, TF
Galon, J
Gnjatic, S
Gogas, H
Kashani-Sabet, M
Kaufman, HL
Larkin, J
Lo, RS
Mantovani, A
Margolin, K
Melief, C
McArthur, G
Palmieri, G
Puzanov, I
Ribas, A
Seliger, B
Sosman, J
Suenaert, P
Tarhini, AAaat8@pitt.eduAAT8
Trinchieri, G
Vidal-Vanaclocha, F
Wang, E
Ciliberto, G
Mozzillo, N
Marincola, FM
Thurin, M
Centers: Other Centers, Institutes, or Units > Pittsburgh Cancer Institute
Date: 3 June 2013
Date Type: Publication
Journal or Publication Title: Journal of Translational Medicine
Volume: 11
Number: 1
DOI or Unique Handle: 10.1186/1479-5876-11-137
Refereed: Yes
Date Deposited: 30 Sep 2016 14:26
Last Modified: 04 Feb 2019 16:55
URI: http://d-scholarship.pitt.edu/id/eprint/29717

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