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Does intra-aortic balloon support for myocardial infarction with cardiogenic shock improve outcome?

Khashan, MY and Pinsky, MR (2013) Does intra-aortic balloon support for myocardial infarction with cardiogenic shock improve outcome? Critical Care, 17 (2). ISSN 1364-8535

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Abstract

Background: In the current international guidelines, intra-aortic balloon pump (IABP) counterpulsation is considered a class I treatment for acute myocardial infarction complicated by cardiogenic shock. However, evidence is based mainly on registry data, and there is a paucity of randomized clinical trials.Methods: Results: At 30 days, 119 patients in the IABP group (39.7%) and 123 patients in the control group (41.3%) had died (relative risk with IABP, 0.96; 95% confidence interval, 0.79 to 1.17; P = 0.69). There were no significant differences in secondary endpoints or in process-of-care measures, including the time to hemodynamic stabilization, the length of stay in the intensive care unit, serum lactate levels, the dose and duration of catecholamine therapy, and renal function.Conclusions: The use of IABP counterpulsation did not significantly reduce 30-day mortality in patients with acute myocardial infarction complicated by cardiogenic shock for whom an early revascularization strategy was planned. © 2013 BioMed Central Ltd.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Khashan, MY
Pinsky, MRpinsky@pitt.eduPINSKY
Date: 6 March 2013
Date Type: Publication
Journal or Publication Title: Critical Care
Volume: 17
Number: 2
DOI or Unique Handle: 10.1186/cc12520
Schools and Programs: School of Medicine > Critical Care Medicine
Refereed: Yes
ISSN: 1364-8535
Date Deposited: 06 Oct 2016 16:24
Last Modified: 04 Feb 2019 15:56
URI: http://d-scholarship.pitt.edu/id/eprint/29751

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