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Conceptualization of molecular findings by mining gene annotations

Chen, Vicky and Lu, Xinghua (2013) Conceptualization of molecular findings by mining gene annotations. In: Great Lakes Bioinformatics (GLBIO) Conference 2013, 13 May 2013 - 16 May 2013, Pittsburgh, PA, USA.

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Abstract

Contemporary genome-scale studies often return a long list of genes of potential interest, and a challenging task is to reveal the major functional themes the genes are involved in at a conceptual level. The Gene Ontology (GO) is an ontology representing molecular biology concepts related to genes and their products, and current annotations from the GO Consortium are highly specific. There is a need for tools that reveal the major functional themes through mining and representing semantic information of genes in an objective and quantitative manner. Our methods provide an objective and quantitative approach to capturing the major directions of gene functions in a context-specific fashion.

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Details

Item Type: Conference or Workshop Item (Poster)
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Chen, Vickyvic14@pitt.eduVIC14
Lu, Xinghua
Date: 26 June 2013
Date Type: Publication
Journal or Publication Title: F1000 Research
Publisher: F1000 Research Ltd.
Event Title: Great Lakes Bioinformatics (GLBIO) Conference 2013
Event Dates: 13 May 2013 - 16 May 2013
Event Type: Conference
Schools and Programs: School of Medicine > Biomedical Informatics
Refereed: No
Uncontrolled Keywords: Gene, Ontology, (GO), mining, semantic
ISSN: 2046-1402
Official URL: https://f1000research.com/posters/1093451
Related URLs:
Additional Information: Competing Interests: No competing interests were disclosed
Date Deposited: 29 Nov 2016 17:28
Last Modified: 25 Aug 2017 04:56
URI: http://d-scholarship.pitt.edu/id/eprint/30132

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